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SNORD38A: SNORD38A is a C/D box small nucleolar RNA (snoRNA) [PMC4052096]. It is annotated to SNORD46, RPS8, and SNORD38A [PMC4052096]. SNORD38A is highly expressed in control samples [PMC6125376]. It is associated with the number of tumor-infiltrating CD8 T cells [PMC8615616]. SNORD38A is one of the four genes that show strong GxE interactions and have single nucleotide variants (SNVs) within the proximal promoter [PMC4052096]. It plays a role in modifications of ribosomal RNA through 2′O-ribose methylation [PMC4052096]. SNORD38A has been found to be expressed at higher levels in extracellular vesicles from the HuH6 cell line compared to other cell lines [PMC5669939]. In Q fever seropositive controls, SNORD38A is down-regulated compared to healthy controls [PMC6518812]. It has been identified as one of the snoRNAs that can be used for the diagnosis of cervical cancer when combined with miRNAs and mRNAs [PMC9774372]. SNORD38A shows enrichment on the polypyrimidine tract (PPT) in splice sites analysis [PMC9226514]. In a normalization panel for microRNA analysis, SNORD38B and SNORD38A are used as small RNA controls for adjusting threshold crossing values between patient groups [PMC4519802].
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Gene Ontology annotations
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