oar-mir-200c: Oar-mir-200c, a member of the miR-200 family, is involved in epithelial-mesenchymal transition (EMT) [Mongroo and Rustgi, 2010; Pan et al., PMC6385976]. In a study on sheep, oar-mir-200c was selected for analysis to validate RNA-seq data [Pan et al., PMC6385976]. Competitive endogenous RNA network analysis revealed that oar-mir-200c targets circRNAs and is involved in various cellular processes [Pan et al., PMC9464909]. Specifically, oar_circ_0007583, oar_circ_0007584, and oar_circ_0007585 were identified as competitive endogenous RNAs of oar-mir-200c that affect the TGF-β signaling pathway and enhance somatic cell reprogramming efficiency in sheep [Pan et al., PMC9464909]. Functional experiments confirmed that oar-mir-200c directly targets the 3'UTR of ZEB1 gene and down-regulates its expression while increasing the expression of E-cadherin [Pan et al., PMC8611307]. Furthermore, luciferase assays demonstrated that co-transfection of oar-mir-200c mimics with ZEB1 3'UTR plasmids significantly decreased luciferase activity [Pan et al., PMC8611307]. In sheep somatic cell reprogramming experiments, transfection with oar-mir-200c mimics increased E-cadherin expression while decreasing ZEB1 expression [Pan et al., PMC8611307]. Additionally, bioinformatics analysis revealed that circRNA.18823, circRNA.688, and TCONS_00428946 mediate the regulation of FGF7 expression by oar-miR-200b and oar-mir-200c [Pan et al., PMC8427949]. The targets of oar-mir-200c were predicted using the miRbase and Target Scan platforms [Pan et al., PMC8611307]. The miRNAs oar-miR-150, oar-mir-200c, and oar-miR-152 were significantly enriched in epithelial development, immune response, and the Notch signaling pathway [Pan et al., PMC8427949].