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Homo sapiens (human) long intergenic non-protein coding RNA 683 (LINC00683) URS00003481EE_9606

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LINC00683: LINC00683 is a long intergenic non-protein coding RNA (lncRNA) that has been implicated in various cancers, including bladder cancer, prostate cancer, pancreatic ductal adenocarcinoma (PDAC), and colorectal cancer (CC) [PMC8504649] [PMC9601640] [PMC9529468] [PMC9086319] [PMC8457683]. In bladder cancer, LINC00683 has been identified as a hypermethylated lncRNA that may serve as a biomarker for prognosis [PMC8504649]. Higher expression of LINC00683 has been associated with shorter overall survival in bladder cancer patients [PMC8504649]. Additionally, LINC00683 has been found to be downregulated in prostate cancer samples and is correlated with patient survival, suggesting its potential as a diagnostic biomarker and therapeutic target for prostate cancer treatments [PMC8504649]. In PDAC patients, LINC00683 is one of the five immune-related signatures used to develop a risk score formula for predicting overall survival [PMC9601640]. Furthermore, LINC00683 is among the lncRNA prognostic genes associated with disease risk in colorectal cancer patients and is part of an optimal prognostic panel for predicting patient outcomes [PMC9529468] [PMC8457683]. These findings highlight the potential of LINC00683 as a biomarker and therapeutic target in various cancers.

Genome locations

Gene Ontology annotations

Sequence

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ACACAUGGCGCUACAUAGAAAGAAUGCCCUGAGGUGAAGGUGACAGCUCGGCAGUUUCUUAAUACCCUGAACUUGAGCGUGGCCUGCGCUAGAGAAAAUACACGGUGCUUCUUAAAAACAAAAGCCAGCAGCCUGCAAGAGGGCUGUGCCUGCGAGUUCCUGGGAGCAGGAGGGGGCUGUUCCUCCGCCCCUGGCUCCAGUUUCACCCAAGUCACUUCACAGCAGUUGGAAGGAGGUCACCAAUUGUUGAGUGUAGGCGGGGGGCGGGGAGGGAGAGGAAGAGGGAUGAAAAGGGAAGGCCCGGGUCAGCUGGGAGAGGAGCUCGCGGGCUUUCCGGCGGGCUGGCCUGAAGUGGAAGGGCCCAGGGCUGCCUGCCACCCUCAGAUGCCACGCAGGUGUUGGGAGGGCACCCGUCUGUGGGCUCAGGGACGUGUUCCCACCGACAGGCACAGAACGGAAAGCACCUUGGGGGAGACGCCCUUCUCCCCAUCUCAGGAGGGAGGCCGGGCCUGCAGACCUCCAGCCCUUCCCCAGCGCUCGCUGUGAGCUCCCCCCCCCCACCCGCCCCCCACGUGCUGGGGAGCAGGUCCGUUUCCCCACCAGUUUGCCUCUGGUCUUUGUGUUUGCUCUGAGGCCAGGCGCGCCCCCUGCUGCAGGCCUGGGCUCCUGUGUGGAGUUCUCCUUUCAGAUGUUGCUAAAAUGUCUUGAAAGGCUGCGGCCACACCAACAGACGUCGUCCGGCCUUCUUCACACGCAACGAAGCGCCCAGGUGGAAAUGCAUGUACCCGCGGCAGCUUCUCGGCAGCGGGCUUCCUGGGACGGAAGACACAGGCUCGCCCGAGGGAGACGGAAGCAGGGGAUCUGCUAGAACUCAGCUCGCCUCCUCCUUUCUCAGCAGGGCAGAGAAUCAUGGGCUUGUGCUGACGAAAGCUCCAGAAAAUGGACUCAUUUAACCUUUCCAAAGAUAUUAUCCAAGCUGCAAAAUCUUGGCAAUCUGAAGACCUUUUAAGUCGAUAUACCAAAGAGCUUUAGUCAGGAUUGAAUGCAAAAUGCCAAAAUUUCACUUUUAAAAUCAUCGUAACAUCUAAAUACAACCUAAGCACACUUGUAAACUGAUGCCGAACAGGCACUUGGAGAGCCCUCCCUGCACCCCUUCCUCGCCCCCUCCUUUGUGCAAAUGCUGUUUGCCCAGAACUUCAGCCACUGAAAAUCCUGGGAACUUUCUCUUCCUGGCUGCCAACCUAGCAGUUUGGACUCACAGACGAGAUUUUUAAAUCACUGAGGGAUUUAAGCCUCUCUGUGUCACAGAAAAGCGAACACCCUCCCAGUUGAAGGUGGCCCCAAAGAUGCGGGCCUGGGACCCAGGACUUCUGCAGGAGAGUGGACGCCUGGGUGCCCCCCGCCUUGCCCUGCACAUGAAUAACAGAGUACACCAGUCAUCAUAAGAAGAAAAAUUCACAUUUAAAGUUUGGAAAGCAACAGGACAAAGGUCUGUCUUCAGUGGUGCGUAGACAUGCUCGUGAUUGAAUUGGAAAUAGUUCUCUUUCCUUCUCUCUGACUUCCUAACUGAAAAGCUGCAGCGUGGGGAGAAAGGCUGCUCAGAAGCCUGGAGCCAGAACACGCACCCCGGCUUUUGCAGGGCCGGCUCACUUGGUUAGAAUCAAAGGAAAAGCCUUGUUAUUUGGGAAGCUGGGCGUCCUCACCAAAUUAGGGGAUUUAAUUUGCAGAUAUCUAAGGAGUGCUUUGAAAUGAAAGAUGAACUAAAAUCUGCUCUGAGGCCCGUGAUUUUUCACCAGUGAAGGACUCUCUUGCUGCUGGACAUACAUGAAAAGCAUCAUCUGAUCUGAAACGCAAGUCCCUGCAAGACAGAGGAGAGACUUUAUAAACAUUUUAUACCAUUCUAUGAAAUCAAUUCGAUUCAGGGCUAGAAUUCAAGAAGUAAUCCAUGGGCAAGUAUAUCUGAUGGUAAACCCAAACGAUUAUAUUGUUAACCUCUUGUACUUUUUUUAAUUUUUUAUUAUUUGAUAUUAUUAUCACAAAAGUCGCUGGAACAGGAUCCAUGAGCUGCUUCUUCACUGCUUAGUGUUUUCAGAAGCUGAUGGAUUAUUAAGCUCCAAUUGAAUACUUGAUUUCCAAUGAUUCCAUUAAUUUUUCUGGUUUGUGGUAGGAUUUGAUUUACUUAUUUUGUACUUUAACACACCAAUAAAAAAUAGAUACUAAG

Taxonomic tree

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Publications