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hsa-mir-1270: Hsa-mir-1270, a microRNA, has been shown to have a significant suppressive effect on glioblastoma multiforme (GBM) in in vivo xenograft models [PMC6592694]. The targets of hsa-mir-1270 and hsa-miR-3177-5p are enriched for alternative splicing, suggesting their potential role in regulating gene expression [PMC8158476]. The upregulation of hsa-mir-1270 has been found to have a significant impact on GBM, indicating its potential as a therapeutic target for this aggressive brain tumor [PMC6592694]. Additionally, the enrichment of alternative splicing targets suggests that hsa-mir-1270 and hsa-miR-3177-5p may play a role in modulating gene expression through this mechanism [PMC8158476]. These findings contribute to our understanding of the molecular mechanisms involved in GBM and provide potential avenues for therapeutic intervention. Further research is needed to elucidate the specific genes and pathways regulated by hsa-mir-1270 and its impact on GBM progression.
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