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SNORA71A: SNORA71A is a type of small nucleolar RNA that has been studied for its role in various cancers. In a study, RNA pull-down and mass spectrum assays were used to identify the binding proteins of SNORA71A, aiming to understand its mechanism in mediating the expression of ROCK2 [PMC9067147]. Functional studies demonstrated that knockdown of SNORA71A inhibited the proliferation, migration, and invasion of non-small cell lung cancer (NSCLC) cells in vitro [PMC6584411]. Furthermore, different expression levels of SNORA71A were associated with significant differences in tumor-free survival time and long-term survival time in NSCLC patients [PMC7537701]. Additionally, SNORA71A expression levels were found to be significantly associated with TNM staging and lymph node metastasis in colorectal cancer (CRC) patients [PMC7559222]. The abnormal expression of SNORA71A was also found to be a potential biomarker for assisting in the diagnosis of CRC [PMC8806983]. Interestingly, SNORA71A was suggested to have a tumor suppressive role in hepatocellular carcinoma (HCC) based on the study's results [PMC7537701]. Overall, these findings highlight the potential importance of SNORA71A as a biomarker and therapeutic target for various cancers.
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