hsa-mir-3165: Hsa-mir-3165 is a microRNA that has been detected in breast cancer tissue compared to normal breast tissue [PMC4289319]. In a study on sepsis-induced acute kidney injury (AKI), hsa-mir-3165 was found to be up-regulated in the AKI group compared to the non-AKI group [PMC5351858]. Additionally, hsa-mir-3165 was one of the eight differentially expressed miRNAs between the sepsis-induced AKI group and the non-AKI group [PMC5351858]. Further validation of these miRNAs revealed that hsa-mir-3165 was significantly up-regulated in the sepsis-induced AKI group compared to healthy controls [PMC5351858]. In another study, hsa-mir-3165 was identified as one of seven novel miRNAs targeting PCSK9, a gene associated with cholesterol metabolism [PMC8310920]. These findings suggest that hsa-mir-3165 may play a role in breast cancer, sepsis-induced AKI, and cholesterol metabolism. Further research is needed to fully understand its functions and potential therapeutic implications.