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eca-mir-17: Eca-mir-17, eca-miR-8908a, and eca-miR-369-5p were used as reference genes in the study [PMC6302407]. These microRNAs have orthologous pre-miRNAs, including eca-mir-17, eca-mir-18a, eca-mir-19a, eca-mir-19b, eca-mir-20a, and eca-mir-92a [PMC3005926]. In a study investigating endometritis in mares, eca-miR-155, eca-miR-223, eca-mir-17, eca-miR-200a, and eca-miR-205 were found to target inflammatory immune response genes [PMC8227551]. These microRNAs were significantly over-expressed in both young and old diseased mares compared to healthy mares [PMC8227551]. This study was the first to investigate the expression profile of these microRNAs in mares with endometritis [PMC8227551]. The relative abundance of these microRNAs was higher in diseased mares compared to healthy mares [PMC8227551]. The study also suggested that these microRNAs could be potential targets for further research [PMC8227551]. The main objective of the study was to investigate the expression profile of these microRNAs and measure the concentrations of IL-6, PGF2α, and PGE2 in serum samples from young and old mares with healthy and abnormal uterine status (endometritis) [PMC8227551].
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