hsa-mir-378g: Hsa-mir-378g is a microRNA (miRNA) that has been analyzed in various studies. It has been identified as one of the significantly upregulated miRNAs in miRNA-Seq data sets [PMC4822037]. Previous studies have shown that hsa-mir-378g is involved in the proliferation, invasion, and metastasis of cancers [PMC6267165]. It has also been identified as a dysregulated miRNA targeting MX1, OASL, RNF2, and UST [PMC5977984]. Hsa-mir-378g has been selected as a candidate biomarker for predicting individual response to TG tablets [PMC5977984]. It plays a key role in the miRNA-target gene co-expression network and miRNA-mediated gene signal transduction network [PMC5977984]. In an independent test validation, the expression levels of hsa-mir-378g were used to validate an SVM-based model for predicting drug response [PMC5977984]. The putative target gene of hsa-mir-378g is UST, which is involved in Chondroitin sulfate/dermatan sulfate metabolism and Glycosaminoglycan metabolism [PMC5977984]. Hsa-mir-378g also contains binding sites for CILP 3'UTR and may be involved in regulating oxidative stress by targeting various genes such as ATG12, ANPEP, MAPK3, or EREG [PMC8261929] and IL10, MMP2 or CREB [PMC7595655]. Overall, hsa-mir-378g is an important miRNA that plays a role in cancer progression and drug response prediction.