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MIR214: MIR214 is a microRNA that has been reported to increase in the oxLDL-induced model, suggesting its potential role in endothelial injury [PMC9199460]. In addition to MIR214, miR-106 is another microRNA that has been found to increase in the same model [PMC9199460]. Inhibition of these molecules could potentially protect against endothelial injury [PMC9199460]. Furthermore, there are six gene-based genome-wide significant association signals at three novel genomic regions: 1q24.3 (DNM3OS, MIR214, and MIR3120), 9q22.32 (MIR23B and MIR27B), and 16p13.3 (LINC00921) [PMC5458088]. These regions are associated with various genetic factors that may play a role in different biological processes or diseases [PMC5458088]. Overall, understanding the functions and regulation of microRNAs like MIR214 can provide insights into their potential therapeutic applications in protecting against endothelial injury or other related conditions.
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