osa-miR168a-5p: Osa-mir168a-5p is a highly expressed miRNA that is encoded on the 5' arm of the precursor osa-MIR168a [PMC6246748]. It has been found to be involved in mediating the OsPTR29 cleavage pattern [PMC6043990]. Osa-mir168a-5p forms a short duplex with a specific sequence, fulfilling the "2-nt 3' overhang" criterion [PMC6246748]. It is expressed at the highest level within the 5'-armed cluster [PMC6246748]. Osa-mir168a-5p has been found to be highly expressed in hybrid and its parents [PMC9549252]. It is also highly expressed in certain lines, while osa-miR168b is undetected [PMC4570225]. Osa-mir168a-5p, along with other miRNAs, has been identified as a heat-responsive miRNA that can differentially alter gene expression by targeting specific HSF or HSP targets [PMC9136941]. It is one of the most abundantly expressed conserved miRNAs in certain conditions and lines [PMC9960954, PMC5578646]. Osa-mir168a-5p has been found to negatively regulate its target HSFB-2c and its expression pattern can be influenced by priming and HTS conditions [PMC8067039]. In certain datasets and conditions, osa-mir168a-5p shows changes in expression levels or inverse correlation with its target transcripts [PMC8067039, PMC5023111, PMC6042804, PMC9597502, PMC7539525].