hsa-mir-548e: Hsa-mir-548e is a member of the miR-548 family, which is characterized by a larger genetic distance from other members within the family, indicating its unique evolutionary path [PMC3468316]. This miRNA has been observed to decrease significantly in cellular levels when HEK293 cells are exposed to lead sulfide quantum dots (PbS–MPA QDs), suggesting its potential role in cellular response to heavy metal exposure [PMC4560511]. Furthermore, hsa-mir-548e is among the miRNAs proposed as exosomal biomarkers for HEK293 cells' exposure to PbS–MPA QDs [PMC4560511]. In studies of congenital anomalies of the kidney and urinary tract (CAKUT), hsa-mir-548e has been identified as one of the miRNAs affected by rare copy number variations (CNVs), which are significant for understanding gene-miRNA interaction networks in this condition [PMC9587983]. Additionally, hsa-mir-548e has been consistently identified across various miRNA databases, highlighting its potential importance in biological research and clinical diagnostics [PMC4359307]. In liver hepatocellular carcinoma (LIHC) patients with varying tumor mutational burdens (TMB), hsa-mir-548e is among the differentially expressed miRNAs that may be involved in the biological processes associated with this cancer type [PMC7355149].