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Homo sapiens (human) GPR158 antisense RNA 1 (GPR158-AS1) URS00000853F4_9606

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GPR158-AS1: GPR158-AS1 is a long non-coding RNA (lncRNA) that has been found to be closely related to the overall survival (OS) of non-small cell lung cancer (NSCLC) patients [PMC5584202]. The molecular mechanisms underlying the role of GPR158-AS1 in cancer still need to be explored [PMC9027133]. Elevated expression of GPR158-AS1 has been associated with poor patient outcomes in lung adenocarcinoma (LUAD) [PMC9027133]. A 4-lncRNA signature, including GPR158-AS1, has been identified as having prognostic value for LUAD based on The Cancer Genome Atlas (TCGA) dataset [PMC6485218]. A risk-score formula for survival prediction was constructed based on the expression levels of GPR158-AS1 and other lncRNAs [PMC5584230]. Higher expression levels of GPR158-AS1 have been associated with shorter survival in NSCLC patients [PMC5584230][PMC5093404]. Although lacking information for calculation, the influences of GPR158-AS1 on prognosis have been clearly demonstrated in a study [PMC5348393]. Additionally, lncRNA KCNK15-AS1 has shown a protective effect against non-small cell lung cancer, while lncRNA SPRY4-IT1 has also been associated with shorter survival in NSCLC patients [PMC5868398][PMC5584230][PMC5093404]. References: [PMC5584202] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584202/ [PMC9027133] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027133/ [PM6485218] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM6485218/ [PM5584230] - https://www.ncbi.nlm.nih.gov/pmc/articles/PM5584230/ [PMC5093404] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093404/ [PMC5348393] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348393/ [PMC5868398] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868398/

Genome locations

Gene Ontology annotations

Sequence

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AAAGAGUAACCAGCCACCCGGGCUUGUAACUCCCGUUCUCGCACUCCAGAUAAGGCGGAGACCACUUGAAGUGGCUCUUGUCCCCGCCGAGCCCGUCCUUGCGCCGCCAGCUGUGGCCCAGGCCCCGGGGCCCCUGAUUGGGGCCGCGGCGGUGUAAGUGGGGCCUCCACUUGCGCCGGAGGCCGUGGAACCACUCGGUCUCCAGAGUGGCGUUGGCCAGGUGGGGUGCGGAGGAGGACAGGUCUUGGAGCAGGAUGCGGCUCUCCUCGCGCGUGGCCUGGAGGAAGACCUGUGGGGCCGGUGCGGACAGCGAAUCGGUGCUGAAGGUGAUGGCCGCCCGGGAGAUGCUGGGCUCGCCCUCCAGAAGGCUCCACACCAGCGCCUGGUACCAAUCCAGGUCGUCCUGCAAGUUCUGCUCCCGCGACUUAUUGCUCUGCAGCAUCACGUUGAGGAAGUUGGUGGCGUGUGUCAGUGUGUCCAGCGCCCGGUGCAAGGAGGGGUGCGCGCUGGCCAGGGCUGGCCACUUCCCCGGCAGGCCCGCCAACUCGUAGCGGCCGGAGCAGUUGGCUCGCUUCAGCUGGUGGGAGUCCCCGGUGUAGAGCACUAUUCCUAGGCCUCCAAGGUGUCUCCUCAAAGACUGGCUGACCCACUUUCCAGAUGGAGCCAACAUCAUCCUCUGUCUCAUCCAUAAAUCAUGAACAGAAGGCCCAGGAAAUGAGAAGCGGAGUCCCCACUGGGAGAGUAGCAGAGCUUCCAGCAUGAGGCCCACAACGAGAUCACAGAAGCACAGCAGAAUUCUCCAGAAAGCCAGUUGUGAUCAAUGGCAGCACAGCCUGGUCCCACAGGAAAUGUUCCUGGAUUUUAAAACACAAAUAAACAGUAAUGCAGAAAUUAGAGAAGAUGUAUCAUUUACCAAAUUUAAUCUGGCACAUUUAAUAAUACAUUAUGAUAAUUAUGGCACCUGAAAGCUAGAUAUAAAUACUCAUUCAUUUGCAAUUCAUUGGCAAUAAUAGUUAUUUCUGAGAUUCCCUCAGACCAAUGAUGGUAAAGAGAAAAGAUAAAGUUAAUGAGCUUCUCCUCUGAGAGAAGGAGGUCACAGGCCACUCUUCCGGUCGUCAUUCCCUAUAAAGGAUUAAAGGUAUGAGCUCAGGGAAGGAUGACUUCCCCCAGUACUUUCUUGAAGUUCUUUUGGAAGAAGAAAUAGUUAGAUACCCUAGAGAGUCUGAUUUUGGUGUUCAUUUAGAAGUCAAAGGCAUGAGGUCAGACCUUGGUCUCAUAAUAGAUUAGCAGCAAGAGAAAUUAUUACUGUGGGUUUUGUUUUUGUAUUUAUUUAUUUAUUUAGACAUCAAGAAACUGUGAAACUGAGCAGCCCUUCAGUAGGAGCUGGUAGGAAAGGCAGCUUGAUAUGUAAGCAAUCUAGAAAAACAGCUGUACUUUCAGUAAUUAAUAAAAUUUAGUCCAAGUAUUUGCCUAAGACUUUUGCUUUUUAGUACUCAUACUUUUUACUACUCAUUCCAAGUAAAUUAAGAAUUGAAGUCGGAAGGGCCAGAUCACAGAAUGUCUCUUAAAUAUAGGCAAAUGAUUCUAGAUUUUAUACAGUAAUUCCUUGAUCACUAAUAAGUUUGUCUCUAAUAUUGACCCAAAGGUGAGGAAAAGAGUAGUUCUCAGACAAAAAAAUGCCCAGGAAUAGGUGUCAACAUAGCCGAAUGACUUGUGAAUUAGUGAAUUCCUACAAGCCAGGACAGAGCUUUUGAAAAUUAUAAUAAAGUUAUUUUCCUCUCCAGUUUUUUGGCAUUGUAUUACAAUGUCUAGGAAGGAAGCUAGGUUUCCCCACCCUCACAUAUACUCCCUUCUAUGAAGAAGGCAGAUAUAGGACAAGGACCAGGACAGUACUGGACCAUAGCACUAAGGGGUAGGCUUUUAGGCAUUAAGAGUGCGGAAGAUAAAAUUUAAAAAUCAAUCCAUCUUAAUCAAUAAAACAUCUUACCUCUGCAUAGUAUACCUACCUGAAUUCCUUUUUUGGAAUCUUUUUCCUUAUUUAAACUUGUCAUUUGAGCAGCUGAAGUAAAAAUAUGGGCCAGGACCCUCUUCUUAGUGAGAAAAUCACUUCCUACCUUCACCCCAACAACAUCGUCACUAAAACAAAUCAAUAAAAACAGCCUCCAAUCAAAGGUCAAAGGAAACCAGAGGGAGCUAAGGGAAAAUGCACCAUUAAGUGGGCAGUUCAGCCUGGUCAUUCUAGCUCUUCCUUCUAAGAGCUUUAGUUUUAAUUCAUAAAUUAUCUCUUCCUGGUUUGGUUUGGCUUUUGUGUUUUUUUUCUUGCCAUAAAAGUGAUAAGGCAUGAAAUUCCAAGUUUAGGGUGUGAGCCUGGGGGAAAAAUUGCCAAGAAAACUAUUUGGUUGCCUUCAGGCUAGGCUUCUAAGUCUUAGGGGC

Taxonomic tree

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Expression New Publications