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Homo sapiens (human) long intergenic non-protein coding RNA 840 (LINC00840) URS000006A9A7_9606

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LINC00840: LINC00840 is a long non-coding RNA (lncRNA) that has been studied in the context of cytokinesis and breastfeeding duration. In a study on cytokinesis, knockdown of LINC00840 was found to double the time required for cells to cleave the cytokinetic bridge, while knockdown of loc729970 resulted in shorter cytokinesis [PMC7160116]. Depletion of LINC00840 led to an increase in the number of cells with cytokinetic bridges, but did not result in multinucleation [PMC7160116]. Additionally, LINC00840 was found to be differentially expressed and differentially methylated in relation to breastfeeding duration [PMC9219990]. In a study on lncRNA expression and colocalization with expression quantitative trait loci (eQTL), LINC00840 was identified as one of the differentially expressed lncRNAs [PMC9545622]. Furthermore, a CpG site on LINC00840 was found to be hypomethylated [PMC7277240]. Finally, LINC00840 was identified as one of the highly connective lncRNAs when analyzing its neighbors [PMC6123437]. References: - [PMC7160116]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160116/ - [PMC9219990]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219990/ - [PMC9545622]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545622/ - [PMC7277240]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277240/ - [PMC6123437]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123437/

Targeting miRNAs 2 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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AACUUCAAUUUUAAUCUGGAUAACGCCAAAGCUUUUCCUCAAAUUCACCCCUGGAGUCAGCUCAUAGAUGCUCUGAUUUUGUCUACCAUUGCUCCUCCUUAAUAUCUCUCGCACAGGUGCCAUUGACCUUUAGAUGGGCUGUACGGUGUGGGGUUCGGUGCCAUGGAUCUGCUUCUCCAGGGACCAGGAUCUUGAGAUCUUCAGGCUGGGUUUCCAUGGAGGCAUGGAGCUGCUUUUCCUCCUUCAUAACUGCACUCAAAACAGCCCUGUUGCUCUAGAAUGGAGACUUGGGCAACUCCUUCUGGCACAGAUUUGUUCACCUCAGGUGAAAUUCAGAUAGAAGCAAGCUGCAGGCAGUUUCACCUCUAAGUCCAUGGGUUCUCAACUGGUAACGUCCUCUUAUGGAUGUUAGCCCAUGAGGUCAAUCCUGUAGCAAUCUAAGGCUUGAGAAAAAUUAAUCUUCUGGAAAAUUCCAAGAAUACAUCUUAGGGAAACUGGCUCUACCUUUAUGACUUGGAUCACACAAGGAUAUGCUUUUCAUCUUGGACUAGAACUGAGAGCCAAUGGAUGUGUUAUCUAAAACUAUCCCAGUGUGUUCACUAUACAGAGGAAGAUUCUGAGAUUCAAGACUCAAGACUGAAGAAGAUCAUUAUUUUUAUUAUUUUAGUCUUAUGCACAAAAUGAUAUCUACUGAAUAAGCAGGUUUUUAAUAGGUGACUUAUAUAUGUUAGCAAAAAUAAACACUUUGUCUUUUAGAUCUAUUCUAGUUUUUCAGUAGCUGUAGACUUAAGUGCUAACUUUUAGCCCAUAGGAUAAGAAGAAACCAAGUCCUAAAAGUAGGCCAGCACCAGGGUUCAGGCCUCUGACUUCAAGCCAAGGGCUCAUCAUCUUGAAUUGCGCACGAAUUUUUACACAGCGCCAAAGGAAACUGCCUGUACUUACUGUUGUAGGUGCUUUGCUGGAUUCAGGAUGCAGACAAGGUCCACGCAUUGUGGUUGGAACAAUGACUAGAUCUUUACCUGGUCCACAGCCCUCCCCAGUCUGGCUGCAACCUCUCAUGAGGCUGAGCUCACCAUGAACCCCUGCUCUAGGCGUCUGCAUAGUGUUCUGUUUGUCCCCGUGACUGUCCACCUCUUCUUUGGCCUGUUGGCAUGCGCUUAUCCUCCAGACCUCAGUCCAAAGUUCAGUCCCGGAGCAGACACAACCCUGUUUGCAGAGAGCCAACAUUCUAAUUGACAGUGCGUGGUGGGAAACAGUGAACCGAGGGAAAGAGUGCCAGUGUUAGAGAGCCACAGUGCAGUGAAGAAGAGAAGGCAAGAGGAUGUGAUGCAAAAUCACAGGACCUGGCUUCCAGACCAUUCUGCUUCCAUGAGAACAUUUCAGUUGAGAACCGGAUGGCAUGAAACUUUAUUGAAGUAUCAGAGAAUCAUUUUCUUAAGAGAUGGUAAUGGAAUCCAUGCAUUUGAAAUAAAUCAACAGAAAAAAAUGAUUCAGAAGAGAGGGAACUAGCCUAAGGACAACUGUGAUAUUGUGAAAUAUAUAUAUGGGUCUUCAUCCUGUGUCCUGGCAUACCUAAAACCCUUGGAAUAUCCAAAGGCAUGCUUUUCAUGUGCAAAUGAUUGACUGAUGUCUUCAGGAUGGAGCCAAUCACCAGAAAUGUCAAAGCAUAAUUAGAGUGUUGGGACUUUCAGCCAUACCCCACACCCCUGACCUUUGGGGAGGAGAGACGGGCAGAAGGUUAAGUCCAUCAACAAUGGCCAGUGAUGUAAUCAGUCAUGCCUAUGUAAUGAAGCUUCCAUAAAAAUCCCAAAGGACUGGGUCUGGAGAGCUUCUGGAUAUCUGAGCACAUGGAGGUUCCUGGAGGGUGGUGCCUGGGGCAGUCAUGGAAGCAUCUCAUCCCUUCCCACAUGCCUUGCCCUAUGCAUCUCUUCAUCUGUAUCCUUUAAAAUAUCUUUGUAAUAAACUGCUAAGCAU

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Expression New Publications