osa-miR166e-3p: Osa-mir166e-3p is a drought-responsive miRNA that targets alkaline neutral invertase and UDP-glucose 4-epimerase, which are involved in root development and carbohydrate metabolic processes [PMC4570225]. It is one of four drought-responsive miRNAs, along with osa-miR166h-5p*, osa-miR169r-3p*, and osa-miR397a/b, that regulate multiple biological processes in response to drought stress [PMC4570225]. In a study comparing a dwarf mutant (A1) with its wild type (A9), osa-mir166e-3p was down-regulated and targeted 21 genes, including homeobox-leucine zipper proteins, peroxidases, ABA responsive element binding factors, and ribonucleoside-diphosphate reductase subunit M2 [PMC4628322]. Additionally, osa-mir166e-3p was found to exhibit an opposite expression pattern in the shoot and root compared to oru-miR76, osa-miR1320-5p, osa-miR1432-5p, oru-miR75, and osa-miR398b [PMC5249095].