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Homo sapiens (human) long intergenic non-protein coding RNA 2575 (LINC02575) URS0000D78084_9606

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LINC02575: LINC02575 is a long non-coding RNA (lncRNA) that has been implicated in various cellular processes and diseases. It has been shown to promote the proliferation, migration, and invasion of Hep-2 and TU 177 cells [PMC8207764]. Additionally, LINC02575 has been found to be positively correlated with the overall survival of patients with laryngeal squamous cell carcinoma (LSCC) [PMC8207764]. In a study focusing on LINC02575, it was identified as KIMAT1 (KRAS-Induced-Metastasis-Associated-Transcript 1) and found to be induced by KRAS, a gene associated with cancer progression [PMC8016872]. Suppression of the KRAS pathway was associated with lower expression of LINC02575 [PMC9861885]. Furthermore, LINC02575 was found to competitively bind with miR-191 in esophageal cancer cells [PMC8486540]. It was also identified as one of the key risk factors in esophageal cancer prognosis prediction [PMC8486540]. Additionally, LINC02575 has been reported to promote the proliferation of laryngeal squamous cell carcinoma cells [PMC8486540]. Overall, these findings highlight the importance of LINC02575 in various cellular processes and its potential as a prognostic marker in different types of cancer.

Genome locations

Gene Ontology annotations

Sequence

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AGAAACUGCUGGAUGCUGAGAGGAACGCAUCAGUGGAAGAAAACAAGCGGCUGGACGUGGAGAGGACGUCAAGGGAGCAUGCCGGCGGAAGAGCACACCACAGACGCCGGCAGGCCACCGAGCGGCAGGACCAGGCGGAGUUUGGCCGGGGCAGUCGGAGGAGAGCUAGGCCACUAAGCAGCUCAACUCCAGGAGAUAAACCAUCUCCCUUGUGGCUCCUCCGUCGGCUGAGAGCUGCUUCCACUCAAUAACACUUUGCACUCGUUCUCCAAGCCCCCGUGUGAUCCGAUUCUUCUGGUACACCCAGGCAAGAACCCAGGAUACAGAAAGGCCUCGGUCCUUUCCACAAGUACCUCUACUUGAGGUACUCAUUGACCUGGUUAACACAAGCUGCCUACAGACGCCAAAACUAAGGGCACCCUGGAACACAGGCUUCAGCUGUAAACAUUCACCCCUGGGCACUGCCGUGGGGUGGGAGCCUGCCUGAGUGUAUGCUCCCCUAGAGGUUUGAGCUGCGGGGCACUGAAGAAGUGAGCCACACUCCCAUCGCACACUGCGAGGGGGACAAAGGAACUUUUCCUCUUUUAACUGGGGCCUCAUCUGGAAUCUCGGAAGGUGAAUGUCUGCCUUCGAAAACCCUACCACCUGUCUUUCUUGUGGAUCACCCUGGCCUGCCAUGCCCCCAUCCUGGGCCUAUAAAAACCCUGAGACCCUAGCAAGGCAGAGAUAGAAGCUGCCGGAUGCUGAGAGAAACACAUCAGUGGAAGGGAAGAAGAAAAGCGGCUGGACAUGGAGAGGACGUCAGUGGAGCAUGCCGGCGGAAGAGCACACCCACAGACCCUGGCACGCCGGCAGGCCACGUAGCGGCAGGCCACGUAGCGGCAGGCCACGUAGCGGCAGGCCACGUAGCGGCAGGCCAAGGCGGAGUUUGGCCGGGGCAGUCGGAGGAGAGCUAGGCCACUAAGCAGCUCAACUCCAGGAGAAAACCAUCUCCCUUCUGGCUCCUCCAUCAGCUGAGAGCUGCUUCCACUCAAUAACACUUCGCACUGAUUCUCCAAGCCCAGGUGUGAUCCGAUUCUUCUGGUACACCCAGGCAAGAACCCAGGAUACAGACAGCCCUCUGUCCUUUUGAUAACUAGAGGGUCUCAUUGACCUGGUUAACACAAGCUGCCUACAGACGGCAAAACUAAAAGAGCACCCUGGAACACACGCCCACUGGGGCUUCAGCUGUAAACAUUCACCCCUAGACACGGCUAUGGGGUUGGAGCCUGCCUGUCUGUAUGCUCCCCUAGAGGUUUGGGCAGCAGGGCACUGAAGAAUCAAGCCACACCCCCAUCGCACACCCUGCGAGGGGGACAAGGGAACCUUUCUCUUUUCAGUUGGUCUUAAUAAACACUGAGUAAAUGAAU

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Publications