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Homo sapiens (human) long intergenic non-protein coding RNA 589 (LINC00589) URS0000CCE0F1_9606

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LINC00589: LINC00589 is a long non-coding RNA (lncRNA) that has been found to re-sensitize resistant breast cancer cells to trastuzumab, a targeted therapy for HER2-positive breast cancer [PMC9617889]. In a study, the potential sponged miRNAs for LINC00589 and their binding sites were predicted using LincBase tools (http://carolina.imis.athena-innovation.gr/diana_tools) [PMC9617889]. This suggests that LINC00589 may function as a competing endogenous RNA (ceRNA) by sponging miRNAs and regulating their target genes [PMC9617889]. Interestingly, the study also detected other novel genes, including LINC00942 [PMC6202402]. These findings highlight the potential role of lncRNAs like LINC00589 in breast cancer therapy and the importance of further investigating their mechanisms of action [PMC9617889][PMC6202402].

Genome locations

Gene Ontology annotations

Sequence

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AUGGGAAGAUGUGCCUACUUCCCCUUUGCCUUCCACCGUGACUGUACAUUUCCUGAGGACUCCCUAGCCAUGCUUUCUGUACAGCCUGCUGAACUCUCUGCCCAAAUUUCAGCUGUCACAGAAUGAGUGAUCCUCAUAGUAUAAUGGAAAUGCAUCAUCUCAGUUUCCCCAUGGCCUGAAUGUCCAUACAAAAUGAGAGCCAGUAGAGAAAAACAGAGGACGUGAGGAGUUUUUAAAAAUUGAGGAAAAGUGGAAGGAAAAGUAAGGAUGAAGGUGAAGAUGAAGGAAUAUGUCAGAGAUGCUAGCACUGGCAUCCCCCACCACACAGUACCAUGUACUGCUAAAGAACUCUAGAACAUACAGGGUGUAGACGGCAGUCUUCUUGGGGAAAAAGAGGCUUCAGGAUUGCAAGAUUUCAGCUACUGUCUCUCCUCGGAGCAGGAUUCCAUCUUUUCCAUGGCUGGGGCCCUUGACACAUGUCACUGUGCACUGCUCUUCUCGCUGGGAAAAGGAAACUGAGGCCCAGAGAGGGCAAGUGAAUUUCCCAAGAGUGUCCAGAUGAUACGGAGCUGAGCUGGAAAGUGAGCCUGGAUCUCUCUGGUUCUGAAAGCUUUGCUCGAAAGCACAGGAUGACACCUCCAUUCAAUCAAUAAGCACUGAGACCCUUCCAUGGACUCAGCAGGUCCUGCUGUCCCUGAAGGUUGACACUCUCAUUUCAAACCACAGCGAGAACCCCAAAAGGAAACAGUGCAAGGAAAAUAAUGUGAUAUUUGAGAGGCAGCAUGGAUUAUUGGGGACAGGGUUCAUGUCCCUUCUCUCCCACACACGUGGCAUGAUGUUAAGCGGGUCACCUCACCUCUCCAGGGUUGUUUCCUCAACUGAGAAAAUGAGGGGGUUGAGAUGAACGCCAGCCCUGGGGUGCUCAAUGCUGCAGUCUAGGGUGGUGUGGACUGGAAUCAGAAUUCUUUCUCCUCCGCUCUGGGUGCUGACACAUGAUCUCUGGCUCUCACUCCCCACCCCUAAUCUUGCCCAUCUGAGUUUCAGGUUAUUUUUUCCUUCCUCCUGCUCUUCAAUUUCCUUAUUGAGGAAGCUCUUUCCUGCUGCCUCUGUCCCCGCUGGAGCUGUUUGAUCCAGUAGAGCCAGUCGAAGCCAAGGGGACCCUGACUUGAAUCUUGCUUUCUGACAUGCUGGCUGUGGCUUGCUUGGGACCUGAAUAAGAGCUUGCUUACUCCCGGUGUUCACCACAGCGGAACCAUGGGUGCAGAAAUGUAAUUCUCAACCAGCCCAGUUUAAUCAGCGAAAGACAAUAGAGCUUGCAGGCGGUGUCAUGCUGAGUAUCUGAACACACCAUGGCUGCUGUCGCCCUUUUCAUUAAAAUGAUUGAAAAUGUAUUUCUAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications