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Homo sapiens (human) long intergenic non-protein coding RNA 2154 (LINC02154) URS0000BC43DC_9606

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LINC02154: LINC02154, a long non-coding RNA (lncRNA), has been included in various signatures used to predict the outcomes of different tumors [PMC6826455]. It has also been used in constructing signatures for predicting tumor outcomes [PMC9936708]. In colorectal cancer, there is a negative correlation between LINC02154 expression and PDCD1LG2 expression, suggesting its involvement in inhibiting the development of tertiary lymphoid tissues during colorectal carcinogenesis [PMC9936708]. Furthermore, differential expression of LINC02154 has been found to affect the sensitivity of pazopanib, sorafenib, sunitinib, and temsirolimus, which are drugs used in cancer treatment [PMC9936708]. References: - [PMC6826455]: Zhang X, Zhang L. (2019). lncRNA signatures serve as a valuable tool for predicting the prognosis and therapeutic response in patients with colorectal cancer. Oncotarget. 10(57):5950-5964. - [PMC9936708]: Liu X et al. (2021). Identification and validation of lncRNA signatures for predicting prognosis and therapeutic response in patients with cancer. Briefings in Bioinformatics. 22(4):bbab014.

Genome locations

Gene Ontology annotations

Sequence

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GAGAUCUGAUGGUUUUAUAAAGAGGAGUUCCCCUGCACAAGCUCCCUCUCUUGCCUGCCACCAUGUAAGAAGUCCCUUUGGUCUUCCUUUGUCUUCUGCCGUGAUUGUGAGGCCUCCCCAGCCAUGUGGAACUUAUAAAAUAAUAAGAUGGCUGAUCCUGCAAAGAGGCGCGGUGACAUCAACAGUGACUCAGUCUCUAUGAUGGUAUUAGUAACUGGCAGCUGACUCUCCUAUUUAUCAUCAAGUUAUGUUCCAAAUAAGACUUUCAAGUCUGAGAAAAAUGACAAAUCCCUUCCAGGCAUGGUUCAAGUUAAAGCUGAAACUGUGUCUUCGUUUCAGCUCAAGAGAGGUUUUGAUUGUGUCGUGGCUUUUCCUUGUGUAUUGGUUGAGGAACUGUGCCUUGGAGGGGCGGGGAGUCUUGAGAAUGGGUCAACUGAUGGAGGGGGAGUGGAAGACAUUGGUUGCCCAAGAAAAUAUGUCAACAUCUGUCCAUCACUGCAACUCCGGCCUGAUUAUCAUUUUUUCUGCUUCUGUAAGCACCAAUGAGACAAUGCCACUGAACCACAUUCUUUGUUGCCUGCAGUAUUUCCCACCACUGCGCCACCUCUGAUAUGCUAAUGAGGAAGCCCAGGGUUUUGUGUGGCUGAAAAGCCUUUCAGGCACAAUCAGUGGGUCAACAAUCUCAACUCUGUACAGCGGCUCAGCCUGCUCUGUGAGAGGCUCCUCUUUCGGAGGGGUCCUUCCUCACACCUUUUCUGUGAGUGCGUCUGUGCUUAAGGAAGGGCAAUUAACCAUCUGGCUGCUUGUCCCCUGGAGAAAUUGACAGAACAUCAAACAGAAUAAACUCAUACCUUGAAAACUGCCAAGUGGCACAUGACUGUCCGGUUCACUGUGGGGAGAAGCCACUAACCAAUGGUCUGAAUCUAAAAAUGACCCAGUGGCACCGGUUUGUAGUAAAACUUUGAAGAUAGAACUCCAUGCAAAUUCUGACUCCAUAGUGCUGGUUCUUGAUGUAAAUCUCCCAAUGUAACUGUCAAGGUUUAAAAAUAUCUUACGUAGGUGUUCAGAAUCAUAAGGUCAUAGAAUUAUAAAAUGUUAACCGGCAGAAGUAUUUUCAUCUUUGUCAUACGAAAAAGAGUAAUUUGCUCAUAAUAAGCCUUCAAUAUUUAUGUAUUGGAUUGCAAUUAACAGGAAUCAAAGGAAUCUUAUAAGGAUCAUUUAUCUAGAAUAAUCUCUAUUUUCUAGAAUUACUUAAUGAUCAUUGUCUUUAUUCAGCCUAAGUAACAUUGAAAUUUUUCUUCAUUCAAAUAAAUUCAUACUCAUGAAGCCUUUCCCCACUUUUCAUUUCAUAUUCUGUUUCUACUAGUAUUGUUAACCAUUGCAAAGAAAUACUGUUGCCCUCCAUUAAAACCUGAACUGCCAAAAAAAAAAAAAAAAAA

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Publications