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Homo sapiens (human) OSTN antisense RNA 1 (OSTN-AS1) URS0000A76A86_9606

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OSTN-AS1: OSTN-AS1 is a long non-coding RNA (lncRNA) that is strongly correlated with certain DEmRNAs and is enriched in T- and B-cell receptor signaling pathways [PMC6753250]. It has been found to be an immune-related molecule with potential immunotherapy functions in triple-negative breast cancer [PMC9091009]. However, there was no significant difference in tumor mutational burden (TMB) between OSTN-AS1 high and low expression groups [PMC6753250]. OSTN-AS1 has the potential to serve as a novel immune and prognostic marker for future research [PMC6753250]. To further validate OSTN-AS1 as a potential immune influencer, the degree of its immune infiltration was calculated using MCP counter in R, which estimated the tendency of residential immune cells to vary with expression changes in OSTN-AS1 [PMC6753250]. Moreover, genes associated with immune function, including OSTN-AS1, were highly positively correlated with each other [PMC6753250].

Genome locations

Gene Ontology annotations

Sequence

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CCUGCCUCAGCUUCCCAAGGAGCUGGGAUUACAGAGACGGGGUUUCACCAUAUUGGGCAGGCUGGUCUCGAACUCCUGACCUCAAGCGAUCCACCCGCCUUGACCUCUCGAAGUUCUGGGAUUACAACUGUGAACCACUGCACCCGGCCCAUAAGUUAUUUAAAUGAUGGAAAAAUUCUAUAAAGAGAAAAUUCCACCUCCUCUACUGUUAGUGGUGAAGCUCACAUAAGAAAGAGCCAGCUGAGAGUCUGUCAAGGGGAGACCCAAAACCAGAGAAACUCCUUUUCUUCUUUGUCUCAAUCACAUCAUUUUCUAGGGACACCAAUUCAUCAAGAAGCAAGAGUUUUGCUGUCAGUUCCUCCUGCAUUCAUUCUUCCUGCUGCCUUGUGAAGAAGGUGCCUUGCUUCCCCUUUGCCUUCCACCAUGAUUGUAAGUUUAACGAGGACUCCCCAGCCAUGCAGAACUGUUCACAACCUUGAAUGGCAUGUUGGCAAUAAAAAGAAGACAAUAAAAAAAAAAAAAAA

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