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Homo sapiens (human) MIR200C and MIR141 host gene (MIR200CHG) URS0000A7645A_9606

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MIR200CHG: MIR200CHG is a microRNA that has been studied for its effects on YB-1 expression and tumor growth [PMC8285504]. Knockdown or overexpression of MIR200CHG leads to a corresponding decrease or increase in YB-1 expression, respectively [PMC8285504]. However, MIR200CHG does not affect YB-1 mRNA expression [PMC8285504]. Additionally, in tumor grafts where MIR200CHG expression is knocked down, there is a significant reduction in Ki-67 expression [PMC8285504]. These findings suggest that MIR200CHG plays a role in regulating YB-1 protein levels and tumor growth [PMC8285504]. Further research is needed to understand the underlying mechanisms by which MIR200CHG modulates YB-1 expression and its impact on tumor development [PMC8285504].

Genome locations

Gene Ontology annotations

Sequence

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AAGAGCGGAGGCCAGGGCGGGCUCUAGGCCGUGGAAUCUGGGGCCUUAAAGCCCCUUCGUCUCCCCAGCACCCACUCUCUGGGGGCAGGUGGGCCCGGUGACAGUAACCUUCAGGGAGCCCUGAAGACCAUGGAGGACUACUGACCAACAACCUCUGACCUUCACCCCUCUGGAUGGGGGACGAAUCACUAGGCAAAGGGGAACAAUGGGAAGGAGACAAAAUGGCUGCCUUUACAGCUGCAGCAAGAUGUGGAAACACUGGUUCCCUAGGCACCUCCAUUGUCUUCCCGCCUUGGGAGCAUGAAAUAAAUAAAGUGUGAAGGGGAACAUGAGGAAGACUGAUCCAAGUCAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications