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Homo sapiens (human) RHOXF1 antisense RNA 1 (RHOXF1-AS1) URS0000812161_9606

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RHOXF1-AS1: RHOXF1-AS1 is a long non-coding RNA (lncRNA) that has been implicated in various biological processes and diseases, including cancer [PMC8700203]. It has been shown to be increased in TMEM176B-overexpressing cells and decreased in shRNA-silenced cell lines, suggesting its potential role in cell regulation [PMC8700203]. RHOXF1-AS1 is a pseudogene that overlaps with EEF1A1P30 and SFR1P1, and is antisense to RHOXF2 [PMC4584094]. In gastric cancer, RHOXF1-AS1 has been identified as one of the genomic instability-associated lncRNAs associated with prognosis and somatic mutations [PMC9082950]. In lung adenocarcinoma (LUAC), RHOXF1-AS1 has been associated with overall survival (OS) [PMC8585772]. It is also one of the lncRNAs associated with microsatellite instability (MSI) in gastric cancer [PMC9978521]. In gastric cancer patients, high expression levels of RHOXF1-AS1 have been linked to poor overall survival [PMC9203952]. However, the significance of RHOXF1-AS1 as an independent prognostic factor may vary depending on other covariates and lncRNAs considered [PMC7822677]. Overall, these findings suggest that RHOXF1-AS1 may play a role in various biological processes and could serve as a potential prognostic marker for certain diseases [PMC8700203].

Genome locations

Gene Ontology annotations

Sequence

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AAAACAGGUACUGAGUAUAAAACAAUAUAAAACAAUAUGAGAGGGUCCGUCUCUUCCCUCACCCUGAUCUCCCCAAAUUUGGUCGAUAUCUAAGGUUUUUUUUUGCUGUACAACUCCUUUUCUGGAGUUUUACUCACUUUCAACAAGGAAGGUGAGUUUUCCUGCUUCCAUGAUGAUGGAGGGCAGGCAACUCCUUUCUGGAGUUUCAGCUCAAUUCCAACAGGGAAGGCGAGUUGGAGUUUUUUUCCUGCUUAUAGGCUGGUAGAGAGCAGUGUUGAGCCUGGACUCCAUUCCUAGAUGCGAUUCCUCCCGUGAUCUCAGUGAUUGUAUCAGGCGAAAACGAGGAGGGCAAAAUACCGUCCAGAUGUAAACUAGGAGCAGCCGCACCAGCAGCACCAGCAGAAUGCCGUGGUAGUGCGGCAGGCCCUGGCCCCAUGGACAAAGAGAAACUCGUCAGUGGCAGUGGCCACGAACUCAGAAAGCCUGAGGACAGUCAGCAGCUCCUCUGGCUCUUCACUUUCACACUGGUGCAACUACAGGAGCUGAAGAACAUUUUUCAACUCGUUCCAUACCCGGACGUGUUAGAUGGAGUCUCCCUCUGUCGCCCAGGCUGGAGUGCAGUGGCGCGAUCUCGGCUCACUGCAACCUCCACCUCCCGGUUUUAUGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACAGUGGCCUCAGGGAUAUGGAAUUAAGAUCCACCUGGUGUGAUGAAUAAACCCAGACUCUCAGCAACGCAGGAAAAAAAAAACAAAAACUGGCUGGCGAUCUGGAGUAAAGGAUCCUCACAUCCACGUGAACCAGGAAACUCUGUGCCCAAAUCGACGAAAAAAAAACACUGGGAGAGCCGAACUAAAAGUCUUUUAGCACGGGUACCAGCCCUAGAAUUUCCAGUACACCAGCAGCAGCCUGGAAACCACAUCCUCAUCAAAAGACAGAAAGAAAAAAACUCGAGCCAGCCUGAGAAGGACCCUAUUUUAUGCUGUUAACCACUGAGACUGCCAUCCUCACAGCUGAGAAAGGAUGGACCCACCAUACUCAAGUCAAGAAAACAUCUUCCUCGUCAGAAUCAUGGGUUACUGUACUAGGAUUAAGCCUUACUAAGUUAAAGUUAAAGAAAGCUUAAUUUUCAUAUACCUUCUAUAUUGCUUCUUUUCCUUUCCUUAUUCUGUUACUAGCUCCUUUGUUAUUAAUGUAACUAAGUCUGAGUCACCUCAGACCAUUGCCUUUUAUGCUUGCUCUGUCAUACCUUGUGGAAAUGUAAAAGAUCAAUGACAGCUAGCCUUUUCACACAAUUAUUUAUGCCUCGGCCCUCUAAUUGACACAGUUACCCCUAGCACUCAUCGUUGUGAUCACCUGCAGCCAAGACGCUGAUUUUCUGCUCCUAUAGCCUGGCAACCUUGUGGUACAUGGGACUACGUCCUUUAAACUACCCAGGAGCAAAGUUGGACUUCCAUGAAAAAGGUUUGUGCAGAUCUAAAACCUCUCAUCUAUUUCACUAAAAGGACUUCCCCUUCUAACUGUCACCCUUACCAAUGUAACCCUGUCCUCUCUAUCACCACCUCCACCUGUCUUUAACUAACUCUAGACCUGUCCUUAAUUGCUUUUAUGGUAUUGGAAUAGGAAUUAAAAGAAAUUAAAGAAUGUGUAAGGAGAAACUCAGUUGUAUGUAAGAAAACCCAAUUCCCCCUGAGAAAGAGAAAGAGUUGGAGUCCUUUAAAAAUUAACUGCCUGUUUUUCUGUGGCUAGUGAGCCUUAUCUCUCCUCCUUUCCCAGACAUUGUGAAGACCCUGUUUCUCUAGCUGUGCAGCUGCAAGGUCACUAGACAGAUAAACUCAAGUUGUAAAACAUGUUUUUCCUUGAAAAGUAAGAAAUGCUGUAAUGCAUUUCUCAAUUAAUUAAAUAACUGUCUUUGUUUCUCGCUUCUGUAAUAUGCUUCCCCCUGCACAGAUCUCCACCCACCCUACAAAAUGCUUAAAAGGUAACUUAACUCUUUGUUCUGGGCUCAGUCCUUUGGGCUGAGUACUGGGCCGGUGCACCUAAAUAAUAAAUAUCUUCCUGAACCCCAAAAAAAAAAAAAAAAAA

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Publications