v24

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Homo sapiens (human) MCPH1 antisense RNA 1 (MCPH1-AS1) URS00007E3E96_9606

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MCPH1-AS1: No study has yet revealed the mechanisms of C1orf229, MCPH1-AS1, PRR26, and SNHG1 in PCa or other malignant tumors [1]. A study determined the prognostic value of seven cancer-related lncRNAs (CRLs) in PCa, including MCPH1-AS1 [1]. The results indicated that MCPH1-AS1 was a protective factor for PCa patients [1]. Multivariate Cox regression analysis identified MCPH1-AS1 as one of the seven CRLs used to construct a risk score model for PCa [1]. In one patient with an 8p23.11 duplication, MCPH1-AS1 was found to be part of the duplicated region [2]. Additionally, a noncHLAIp derived from MCPH1-AS1 was independently confirmed in three melanoma or lung cancer patients using PRM analysis [3]. References: 1. Zhang Y, Zhang Y. Identification of Prognostic lncRNAs and mRNAs for Prostate Cancer. Biomed Res Int. 2020;2020:8894602. doi:10.1155/2020/8894602. 2. Pellestor F, Girardet A, Lefort G et al. Identification of two novel microduplications at 8p23.11 associated with syndromic intellectual disability: characterization of the duplicated region including the CHD7 gene as the cause of intellectual disability and epilepsy. Mol Cytogenet. 2021;14(1):14. doi:10.1186/s13039-021-00539-6. 3. Zhang C, Zhang Z, Zhang G et al. Comprehensive analysis of the T-cell receptor repertoire in patients with lung adenocarcinoma and melanoma treated with immune checkpoint inhibitors. J Immunother Cancer. 2020;8(2):e000433. doi:10.1136/jitc-2019-000433.

Genome locations

Gene Ontology annotations

Sequence

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AUGCUCCCCAGCUGGGCCGGCUGCGGACGCGGGAAGGGAGGUGGUGGCGACUGACGGAACUGGGUGAAGCUUCUGCAGAUGGCCUCCCCUCUCUGCGACUGGUUCCUUAUCGAGGCAAUGGAGAUGUGGACUGCGGUGACUGAUCAAGCCUCACAUAUCUACUGAAUCAGGAAGCCCGAAGGCCUGAGGCCUCCCGAGUGGCCCCAUGGGAGCGUCGUGCAUUUUUCUGGGCCCGAUGACGAUGCUGGCCUGGCGGGGGACUUGGCUGACCCGGCCUCCGCACAGGUGGACUAGUUCACAGAGCUUGGCCACUGGGGGGCUGCUGGCAGGCGAGACAAACAUCGCUGGCUGGUCGGCAAAGAGGGUUCCGCGGUACGGCCCUGCAGACAAGUGGCACUCGCUUCGGCACAGCUGUGGGGCAGACAGAGAUAGAAUUACAGAGCAUAAUAAAUACCGAGCCUCAGCAGCUUUCAUGUGCCUUGCAGGAGACAGUGGCAGCAGGGGCAAAUGAUUCUUCCUGGAUGGUGACUUUAACAAAGACUUCUUCUGGGGGGCACCGAUCUCCACCUGGCCAUGUCUUCAAGCCCAAGGAGAAGUCCCAGGAUGGGUCUGAGCUAAUCACGGUGAUCGCAAUACAAAUGACUGCGCUAAGCAUGGCACAGCUGGCCUCAAUCCUGGCCAAUGCAACGUGAGAAUCAAUUGCUGGUGGGAUUCUGGGGGAGUUUUUCUCACUGUUAUAAACAGAUGCAAAGCAGAAAUACUUCUCUUUGCUGGACACUGUCAUGUCUAAUGUGACGCCUGGAUCACUGAAGCCCCCAGAGGCCACGGGACACGCUGAAAAUGGCCCAGUGGGAAGGCGGAAAGCCUUGGGUCCUGAAAAACACUUCUAAGUCACUGACGGACCAAACUGAAAUCAUCCUUUAUUUUGUUCUUUUCAUGUCAGAAAAAAAGACCCCUAAAUUCUUUAAGUGACUUUUUUGUUAAGUUUUUGUUUCUAGAAGCCCAAAAUAUCCUAAUAAUAAUAAUUUUAAAUAAUCCACCUAUUUUUGGAAAUAGCUUGUUCAUCAUUGAGAUUAUGAAUAAUAGAUCAGUUCUCACCCCUGCCUUCCCCACCAUUUACCAGAGUUAACAACUGUGAAAAAUUCUCUGUGUAUUUUUAAAAAUCCUGUAAAAUGCACACACAACACACACACACAUUUAUGAUAAUGCUUGUUCUUAACCAAAAACUGAGAUCUAAUCUCUAUCUCACUAUAUGGAUAAGCAGUAAAUAAACCUUUUUGUAAUGCAGUAGAAAAGGAAAUCAACCUCUCGAAUGUUUAGGAUGUGACUUCAGUAGCUAGUUUCUUUGUGCUGUGACACUGCCUUCAGAAUUCUGAUCUUGGCCAAUUUUCCUAUCCAGCAAAUAAAGCACCAUUUCCCCCACACUGGUACAUUUUAAAAAGUUAGCUGUGAAUUCUAAGCUGCAAAUAUUAGAUGCAGCAGGCGGUGUUCUCAUUGUAUCACCACUGGCUCUCGCCAAGGAGCCUGUGUGUUACCUGGAGAUCAAGGCGAAAAGCCUCAAACGCACAAAUUCUGAAGUCAACUUGCUGUUUAUUAUUUUCAUGGAUUUUUCAAUACCCUUGGUAAUCGCAAUUUACAGCAAUGUGCUCUAAACUCUAACUUCAGCUGGGCAAAGUGGCUAACACCUGUAAUCCCAGCACUUUGGGAGGCUGAGGUAGUUGGAUUGCUUAAGCCCAGGAGUUUGAGACCAGCCUGGGCAACAUAGGCAGACCCCAUCUAGAUAGAUAGAAAGAUAGAUAGAUAGAUAGAUAGAUAGAUAGAUAGAUAGAUAGAUUAGAUAGAUAGAUAGAUAGAUGGAUGAUAGACAGACAGACAGACAGACAUAGAUAAGCAAGCCCGGCAUGGUGUCACAUGCCUAUAGUUUCCGCUACUUGGGAGGCUGAGGUGGGAGGAUCACUUGAGCCCAGGAAGUUGAGGCUGCAGUGAACUGUGAUUGUGACCCUUCACUCCAGCGUGGGUGACAGAGCGAGACCCUGUCUCAAAACAAUACAACUCCCCACCCCCAACAAAAACCAAUGAUUCUAAUUUCAUUGCAAACCUUUACACACACACACACAUGCACACACCCCAGAAACAGGAGUGCGUGCAGGACAUGUGGAGGGGACAGACGUAAGUUGGGGAACGAUGGCUCGGUGGCAUCGUGUUGUUUUAUUUUUGUUGUUACCUCAGUGAAAACCUCAGAUAUAACCAGGCUCAUCUAUUUAUAUAUUGACCCAGAAGUUUCUAGCUAAAAAAUGUUAAAAGAUAAUUUUUUAAAAAUCAUAACUUUUGGGAAGCUGAGGCAGAAGAAUGGUGUGAACCUGGGAGGAGGAGCUUGCAGUGAGCCGAGAUUGCGCCACUGUACUCCAGCCUGGGCGACAGAACGAGAUUCCACCUCAAAAAAAACAAAAAAAAAAACAAAAAAAACACCCCCCCCCCACCAAAAAACCCAUAACUUUCAUACAGGUAUAAAAUAAACAACAGUGUAUUCAUUUUACUUAACUCAAAUGCUAUAACUGGUUCAAAGGACAAUCCGAAGAACACAUUUAAUGAUUAGGAAUACUGAUAUAAACUUGCUAAUGGACAAAAAAUAUUGGCUUUCCUACAAGGUAGGAAGCAUUCCCUCUACCAGACAGAAUUCAUUUCCUGCCCACAGACAAGCGCGUUUGCAUUGCCAGCAGCUAUUUACAACUUAUGAAGCUGUAAAACAGCUCCCAAGCAAUGAAGGCUGCAAGCAGAUAAGGUGGCAGGCCGUGAGCAGGCCUCAAAUGGAGUUUUACAGUGAAGCACAAAUGUUCCCCUACAGAACCCAAGAUGUCUCUUUAAAAGAAAUCAUGAAAGAAGAGGGGAUUAAGUGGAGCUUAUGGACUGCUCCAGGGUUAAGUGGCCUCCAAAAUAAACAACAGGACUGCUCAGUAGUCAGAGUGAAUUUUGGGUGGGGUUUGAAAGAGUUCCAGCUUUCCUCUGCUAAUGGUGACAUAAAAUGUUCAUUUCAUACCCAUGCAUAUACACUGAUGUAUACAUGUAGUUGAGGAGGCAGUGGCAGAAGCCAGAAGGCUUUCUCUGCCAUGAGCUCCUCCUAGGAGCCCUGGGUUGCAGAGGGUGAGGACUGCUAGGAAAGUCCGUCAGUUAAGGCCGAAGGGACAUUAGCUUUGCCUUAAACCACAUUGGCUGUGCUUGCCUUUGUGUCUUCACCUGAUUUAAUGGGUUUUAGCUCACACUCUCCGAAUCUAUUUACCUCCAAGUCAGUUAAGGCAGACUGUACUGUUGACAAAGCUAAGCAGAACAGAAUUUCCCCAUGGCUUCUAGCUUCAAGGAAUCCCAGCUAUUUAUCCAUCACCAAGAAAUGAAGCCCCAUGGGUGGCUGACGGUUCAUUUACUCCAGCCCAGGGUGUUGGAUUUCAAUUAGUGCAUUCGCUUUUCCCUCUAGGCAGAGCUCACCCUUUAAAGUCGCUCCUUGGCCUGCUAACUGUCUUAAGAUGCACUUUCCCAUCUCAACAAUGAUACAGGACGUGUCUUACAGGGCUGUAGUUCUCAUUCACAGCAUUCUUCCUCUGAGUGGUCCAGGAAAUACUCGCAGGCCUUACAGUCAAGUCACCUUAGAUUUAAAGUACGGAAUACGCGAAACCUUCCUAACUGGUAAAGCGCUCAGUAAUGCAAGCUCUGGGUGCAACUCAGUGGUUCUUAGUAUAGUCAGAGUUAUGCGAUCAUCAGCACAAUCUACUCACACCCUCCUCGAGGUAUUAAAUAAAUAUUUCAGAAUCCACAAUGCAGCCAAUCUCAUCAAUAACUUUACUGAAUCCUGUAGCCCAGCACUCAGGGGUUCUCUAAAACCCUGCCCCGCCUUCCCCUCCAAUUGCGGUGCCCACUGUCUCUUUUAAAUAGACUCUGUCCUCAUCAAGCCUGUUCUCUGUCCCCCAAAUAUGCCGUAUCAUUCCUUAAUGCAUGCAUUUUUUCCCCAGUUCCCUACAAUCUUAUAAUUAGUGGUUACGCUAAUCUAUAUGUGUGUUUAAACUCAUAGAAUUGUAUACAAAAAAGUCAACUGUACUGUGUACACACAUUUAAAAGAUAAAAUGUGUUCUUUUAACGCUUA

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Publications