v24

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Homo sapiens (human) RGMB antisense RNA 1 (RGMB-AS1) URS000075F05F_9606

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RGMB-AS1: RGMB-AS1 is a long non-coding RNA (lncRNA) that has been found to play a role in various biological functions and diseases. In lung squamous cell carcinoma (LSCC), RGMB-AS1 has been shown to regulate cell proliferation and invasion through the miR-22/NLRP3 axis [PMC7303144]. Additionally, upregulation of RGMB-AS1 is associated with clinical severity and poor prognosis in lung adenocarcinoma [PMC6884071]. In lung adenocarcinoma, RGMB-AS1 is also implicated in the regulation of disease progression [PMC8798374]. However, no significant differences were observed between RGMB-AS1 expression, RGMB expression, and gender or age [PMC4460650]. In nasopharyngeal carcinoma (NPC), RGMB-AS1 has been found to directly bind to FOXA1 and regulate NPC biological function and epithelial-mesenchymal transition (EMT) through this interaction [PMC8973592]. RGMB-AS1 is a lncRNA that has been shown to have functional implications in various diseases. In LSCC, it regulates cell proliferation and invasion through the miR-22/NLRP3 axis [PMC7303144]. Additionally, upregulation of RGMB-AS1 is associated with poor prognosis in lung adenocarcinoma [PMC6884071][PMC8798374]. However, no significant differences were observed between its expression levels, RGMB expression levels, gender or age [PMC4460650]. In NPC, it directly binds to FOXA1 and regulates NPC biological function and EMT through this interaction [PMC8973592]. Word count: 200

Genome locations

Gene Ontology annotations

Sequence

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CAAGCUCGGGGCGGUGUUGGAAAUCUGAAUGUCACCCGCGGUCCGGAGCAGAUAGGAUGGGCUGGGAAGGUACCCGCGAACUGCCGCCGGAAUUCGCUGGCAGCUGUGCGAGGCUCAGGUGUUCUAGUUUGACAUUUCCCUUCCUGAAAGCGGCAAGGAGAGGUCUAAGAGUGGGCAAACUUCAACGUUCGGUUACAGUGUAAUUAAUGAGAGUGGUGGGUUUUUAUGCAGUGUAAUUAUGCCACGAUUUGUUGUUGCUCAGUGGCUUUUUCACAAAUUUCUACAGAUUAUUUAAAUUUUCCACAAAUUUCUACGGAUUAAUUCAAUGGCAGCUCACUUUCUCCUUUUAUGAUCGGAUGGGUCCGAAAGUGAGGAAAAAGACAAUUGUCUACAAAGAAAGAGGCUGCCAAGUGGAGACAGAAAAGCAGUUAUGAGACUGAUGAUAGAUUCCAAUUUGUUAUCGAAAGGAAGGAGGAGACCUGAACAGUACAUCCGGAGAAUCCAGCAAAGCAUACUACGGCAUGAACGUGCAAGUGGACAGAAUUAAAACACAUGCCAGAAACACUAAUGGAUUCUAAACAAGAUGCAGUUUCAUUUCCUGAGCCUAUACGUGAUGUUUUUAACUGUUCUCCAGUUAAUAUGUCUCCAUUUCCAGAAAUCUAACAGGAGAAUCUCUGACUGCUUAACAGAUCACCUAAGCUUGCGAUUUGUGCAAUCCUUUCUAGAGUAAGGGCUCCCCGGCUGCUCCCCGGCCACUGUGUACCCAAAGCAGCGGCUGAAAUAGCCCGGAGUCCAACAGCUCAGCGUCAAGCAGCUCGUGGUUUGUACUUACAUCAUUUUUUUUUUCAGAGCAAGAGUGAAAGUUUAUUAAAAAGCGUUAGAACAGUAAGGAAAGGAAAGGAGAGAAAAUAAGGAAAGUACAACUUGGAAGAGGGCCAAGCGGGCGACUUGAGAAAUCAAGUGCCUGUACUUACAUCAUUCUUAACCCUUUCGCUCCUGGAGGGGGCUCAGCGGGAUCAGGGGGCCCCUGAACUUCGGAACACGCAGGACCUGGGUGUGAGAGAAGAGUCCCAAAGCUUGGCGUGAGCAAUGCACUCGCGGAGGGAGAGAGCCCGGGGCUUGCGGGGGGCUCAUCACCCGCUCGUAGACAACGGGCCCCCGCAAUCCCUGCGGGCUCCGCCGCUGCUCUCACCGCUCAAAACGGCAGGUGCAAAAAGCAUUUGGGAGCCGCUUGCCAGCGCGCGGAGGUAAUGCGCUUCCUGUCCAUUUAUCUCAGGAAACCAGUGCAGCCUUCCCUUCGAAACAAAAUUAACCUCUCAUUAGCCAGCCACUCGCUCCCAAGAAGGCCUUAAAAGCUUUACCAGCUCGCUAAUGUAUUUAGGCUUUUCUUCCAGGCAAACGCAGCCGCCGGUCUUGACUGCCAUCGCCCAAGGGGUUCCUCUGGGCUCUCCCGCGAGCCAACAGCCGACCUCUCUCCAGCCUAGUCUGGGAAACUCCAGCCAACCCAGGAUCCCAUUUUGUAGUCCCGGGCAGACCCGAAACCCCUGAAAGAACUCCACUCCAGAAGACGCCAGAACAAGUUCCCACGAAUUUCAUGGGCGCCCUUCACAUGAAAACCUCAGCUCCCCUAUCCUCAAGGAACGGGGAAGGGCGCCGGGGAGGGACUUCGGUGGCCAGCUGUCCCUGGGUCGUGGGCGCUGUUUGCUCUGCGGAGCGCCAGCCCUGCACACAGCGGGUGCGGGAAGCGUUGAUGGGAGGCUGGAGGGCGGGGUGAGCGUAAACUAGGAUCUAGCCGGUUCCAGGCGUGGAGAAUCAAAUGUGGUCCUAGAUCUGUAAGUUGCGAAAAGGGGCUUUUGGGAGCGUCAGAGCUUUCUCACUCCGGUCCCCCGCCGCCUUGAGGCUGGCAGAUUUAUACCACACAGGUGGAUGGAGACCUAAACAAAACAGUCCCGGCCGCUGCCUGCCGCUCGCCCCCCACGUCCCCCGGGCCCACCGCAAACUUCAACAAAAUAAACAACUCACCACAGGCAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications