v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) long intergenic non-protein coding RNA 1433 (LINC01433) URS000075ECD9_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LINC01433: LINC01433 is a long non-coding RNA (lncRNA) that plays a role in regulating the proteasome-mediated degradation of the YAP protein [PMC6778481]. When LINC01433 is silenced, the expression of YAP protein is significantly increased, suggesting that LINC01433 depletion attenuates the degradation of YAP [PMC6778481]. Additionally, LINC01433 knockdown has been found to enhance the sensitivity of gastric cancer cells to DOX (doxorubicin) and DDP (cisplatin) [PMC7251695]. These findings indicate that LINC01433 may have a role in modulating cancer cell response to chemotherapy drugs [PMC7251695]. Further research is needed to fully understand the mechanisms by which LINC01433 regulates YAP protein degradation and its potential implications in cancer treatment.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
GGAGAAUUGGUUGCAUGGUUUCUCGUGCUGUGGGCAUCAGGGACUUCAGGUGAAGGUAUUUAGCUGUGGCUUUGUGCAAACCUCAGAACUGUGUCCUCCAAGGGCCUGGGGUAUUUGGCAGGCGCUGUCUCUUGCUGCCUUUGCUGCUGUAUGACAGACAAAAUAGAAGCCACCUGGAGGCAACUUCCUCACCCAUCGACAAGCUCACCAGCCUUCAUGCCUGUCCUUUGGAGCUUCCCUGCAGACAGUGGCAGCCACCUUCCUCGGGAACCACCUUCCUGGGCCUCUCCUUCAGUCAAGCUGCACAGCAGCAUUUUCUACACUUGCUCUGGCGGCAUCCUCACUGUCAUGCACUAGCGGUUGUUGGUGAGGUUCUUCAGGCUGCAGAUGGAGACAUGGGAAGGGCUGGACUGGCUCCCCUUCUCACUGUGGCUGGGCAGGGUAGGGGGUACCCCGGCUUCCAGGAUCUCUGGAAGCAAGGACAACCUCAAGGGCUGAUCCACAUCCUCUGGUGCCAUCUGCCGCCCAGAUGGGGACACAGCCCUCUUGCUGCACCGAGAAAAUGUGUGUCCUGGAUUCUCCGUGAGCUUUUCUGAAUUAAAACAAACAACAUAAAAUCAUGGGAGUGCCUUUAAUUACUGUUGAAUAAGUGAAUAAAAUAAGAUUAUAAUAUUCUACAGUAAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications