MIR3916: MIR3916 is a microRNA that has been found to be positively correlated with genes B3GALT2, CDH10, NELL1, OCLM, PRKAR2B, TREM1, and USP46, and negatively correlated with genes AEBP1, CDH6, HSD17B2, LUM, MS4A4A, PTN and RASSF9 [PMC8325821]. While TREM-1 has been implicated in high-glucose-induced macrophage phenotypic transformation in diabetic kidney disease (DKD), there is no reported evidence on the involvement of CDH10, MIR3916 or the other genes in DKD [PMC8325821]. In a study on mismatch repair (MMR) patients and MMR+ patients, MIR3916 was found to be highly expressed in MMR+ patients [PMC6036478]. Additionally, MIR3916 has been identified as a regulator of desmosome destabilization during aging by targeting JUP,DSC2 and DSP genes [PMC8282276]. Furthermore,MIR3916 has been implicated in the regulation of calcium handling through its targeting of ATP2A2 (SERCA2) and CASQ2 genes [PMC8282276]. In fact,MIR3916 was found to have the largest contribution in potentially regulating 63% of cardiac genes across various functional categories [PMC8282276]. Lastly,TNNC1,TNNT2 ,ACTN2 ,ACTC1 ,and TPM1 have also been identified as mirror targets of hsa‐mir‐6080 and MIR3916[PMC8282276].