MIR372: MIR372 is a microRNA that has been found to play a role in tumor development and progression [PMC5564752]. In a study, it was observed that the binding of the P21(WAF1/Cip1) protein to the Pim1 promoter DNA probe was significantly reduced in cells treated with pCMV6-AC-GFP-JMJD2A, rLV-JMJD2AΔ, and rLV-JMJD2AΔ plus MIR372 inhibitor compared to control cells [PMC5564752]. This suggests that MIR372 may be involved in regulating the activity of JMJD2A, a protein associated with tumor growth [PMC5564752]. In fact, combining JMJD2A knockdown with blocking MIR372 has shown promise as a potential treatment strategy for tumors with over-activated JMJD2A [PMC5564752]. Additionally, MIR372 has been implicated in the silencing of LATS2 expression, which is a tumor suppressor gene involved in the Hippo pathway. This silencing has been observed in testicular germ cell tumors [PMC8063430]. These findings highlight the potential significance of MIR372 as a therapeutic target for cancer treatment and suggest its involvement in multiple pathways related to tumor development and progression [PMC5564752][PMC8063430].