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Homo sapiens (human) small nucleolar RNA host gene 7 (SNHG7) URS000075E30B_9606

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SNHG7: Small nucleolar RNA host gene 7 (SNHG7) is a long non-coding RNA (lncRNA) that has been implicated in various cancers, including prostate cancer [PMC7035107]. SNHG7 has been shown to play a role in cell apoptosis and chemoresistance in pancreatic cancer [PMC8494469]. It is regulated by insulin-like growth factor (IGF) and is involved in cell proliferation [PMC7244715]. SNHG7 has also been implicated in gastric cancer, colorectal cancer, hepatocellular carcinoma, neuroblastoma, and breast cancer [PMC7453396] [PMC9209656] [PMC7388098] [PMC7732589]. It interacts with microRNAs to regulate gene expression and has been shown to mediate chemoresistance and cancer stemness in breast cancer through miR-34a sponging [PMC9178731] [PMC9103444]. SNHG7 is also involved in liver fibrosis progression by modulating Wnt/β-catenin activity and NLRP3-dependent pyroptosis [PMC7028920] [PMC8634266]. It interacts with miR-9, miR-29b, miR-34a, miR-193b, miR-485-5p, and miR-186-5p to regulate various cellular processes including proliferation, migration, apoptosis, autophagy, stemness, and pyroptosis in different cancers [PMC8641992]  [PM7244715][PM9103444][PM8652206][PM6996990][PM7049860][PM7453396]. SNHG7 expression levels have also been associated with clinicopathological parameters such as tumor size and metastasis status in colorectal cancer patients [PM6029165].

Genome locations

Gene Ontology annotations

Sequence

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CUCUGCGUGCGCCGGAGGCUGCCGUGGCGGGUGGGCCGCCUGACUUCUCCUCCCGGCCAGUUCUCGAGCGCCUCACCGGGCCUCGCCCUGCAGCCUCGCUCUCGCUGGCGCUGCGCGGCCUAGGGGACUGGGCUGCUGGCCUCCGGGUGCGGGGUGGGGGCAGGCUCCGACCUGGGGCGUCCUGGCCGCGCGAGCCGCGGGAUGGGGGCCCGGGCCGCGGAGGAGGCGCCGCUGGUGUGUCCCUUGGUGGAGAGGGCGCUGCCGGCCCUGCGCGGUUUCCAGCCAGGAAGCUUCGGGAAGCCUGGACGUCUGCUCACUGGAGAUGACACGUGCGUGGGGUGUUGGGUAAGUUGGUGCAUUGGAGCUGGAACAGGGUCAAUCCUCCAAUGUAACUAAGCCCUCCUGUGCAACAUCUUAAGUGACUGGAGGGACCAGUCGGUCUUGUGUUCACAUUGAGGCUAGAAGCUGUCUCCAGGGGAGUAAAAACGGAUUAUUUAGUCUUCAACAGGACACUGCCCCUAGAGGCGUUGCAGCUGUGGCUGCCGUGUCACAUCUGUGUCAUUAGGUGGCAGAGAUUAGAGAGGCUAUGUCUACGCUCAGCGUUCUGCCCCGUGAACGUUUGAAUGUUUGAUAGUCUCACACUCCUGUUUUGUGGACAGGCAUCUGUUUUCCUUCGCUGGUAUCUGGGAGAGAGGGUGGGCCCUGUGAGUGGGCUUUCUAACUCUCGCGCUGGGCUAGGCUGGCCUCUAGGGGUCUGAAGGGAUAGUGGGAAGGUGGAGGGUGCCUUCACCAGGAGCAGCCUUCAUGAGUGAGUUUUAAGAACCUGUGAGGAUCGGUCAGGUCAGGUGAGGUACGCGCUGGAUCAUGCCGUACACCGUGUCAGGAUCACGCAGGACAGGACUGGGGAAGGGUUUGCUGGCGUCUCGGUUAAUAGCAGUAACGGCAGCCGCUUGUGUUCUUGAUUCUUUGCCAAGCAUUCUUGUUAUUUAACACGGGAAGGAGGUGACUUCGCCUGUGAUGGACUUCCAGUGUGAGCACUGGCCAGAGUGACCAGGCUGACCAGCACCAGCCCUGAUCCAGGUAAGAGGUGAGGCGGAGGCUUGCCCUCCUUCCCUGCCUGCCGGGUGCGUGUGAGCGGCUGCCCUGCGGAUGCUGUCCUGGACCUGUUGGCACCACAGACAGUUGCUCUGCUGUGCCUGUGGCCUCGGGGCAAAGAGAAAGUGGCGAUUUCUACACUCAGUGCUCGGGAACCAGUGGGCACUGAGAAUGGUUUAUGGCCUGACAUUACUUGCAACCAAAGCCAGGCAGCAUUUGGAUUUUCGCUUUUGGAAACCACCUUACCUGGUUUGCUCCAUGAGGGAGGGGCAGCAACAUCGCUGGGAACCCUGAGGUGUAGAUAUGUAUAAAUGAGCUGUGUGUGUAUCUGAAGCUCGGGCACUUGUGGGGUUACCAGGAGUGUGCGUCUCACUCCCAGGCCUCGUUCUGGAAACGAUUCUGUAGGUCUGUCUGGGAGGCCUUAGGCAAGUUUGAUUAAGAACAGUCGAGCUGGAUAAACAGGCUGUUCCUUGUCCAGCACUAGUCAUCCCAGGGGGGCGGGGGCGGGGCUGCAACUCCUGUGCACAAAGGAAGGGCCCUGGGUAGGGGUCAGGAGCUGCCUUGCCCAGAGAUGUGUCUGGGUCACUUUGGAAACAGGAAUCCUCUCCCCAAAAUGGGUAGCAAUGGGGGUACAGAGGCCAAAGACGCAGCUGCAUGUCCUGCAGUGCCUGGGACGCCCCGUAGUGAAGAGUGAUGUGGCCCAAAUGUCAGCAGUGCCAGUGUCAGACUCCUGCUAAGAGACAGUAUCAAGAAAGAUAACUUCAAAAUACACUUUCUGGAGGCCUGGCGCGGUGGCUCAGGCCUGUAAUCCCAGCACUCUGGGAGGCCAAUGCAUGUGGAUCACCUGAGGUCAGGAGUUCGAGACCAGCCUGGCCAACUGCCUGAAACCCCAUCUCUACUAAAAAUACAAAAAUUAGCCAGGUGUGGUGGCGCAAGCCUGUAAUCCCAGCUAUUUGGGAGGCUGAGGCAGGAGAAUCGCUUGAACCCGGGAGGCAGAGGUUGCAGUGAGCCGAGAUCGCACCACUGCACUCCAGCCUGGACAACAGAGUGGGACUCUGUCUCAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications