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Homo sapiens (human) long intergenic non-protein coding RNA 2325 (LINC02325) URS000075DF4F_9606

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LINC02325: LINC02325 is a noncoding RNA that has been found to be located between RNA gene ENSG00000285584 and noncoding RNA LINC02325 [PMC9968656]. In pancreatic cancer (PaCa), LINC02325, along with other IRlncRNAs (FNDC1-AS1, ZEB2-AS1, and TEX26-AS1), is highly expressed in the high-risk group and is associated with a worse prognosis for patients [PMC9676238]. These IRlncRNAs are also positively correlated with CA199, tumor size, tumor stage, stromal score, immune score, and ESTIMATE score [PMC9676238]. In addition to pancreatic cancer, LINC02325 has also been found to be upregulated in breast cancer, stomach cancer, cervical cancer, colorectal cancer, and esophageal cancer [PMC9676238]. LINC02325 has been identified as a potential prognostic biomarker for pancreatic cancer and may serve as a therapeutic target for individualized treatment [PMC9676238]. Furthermore, LINC02325 has been shown to have a predictive effect on the 5-year survival prognosis of pancreatic cancer patients [PMC9676238]. It is worth noting that the specific mechanism of action of LINC02325 still needs further study [PMC9676238]. Additionally, in head and neck squamous cell carcinoma (HNSCC), high expression of LINC02325 is associated with poor survival [PMC8645855].

Genome locations

Gene Ontology annotations

Sequence

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ACAGAGGGAUCCGCCCCUUUCCUGGCUGCCUACACAGAAAGCAGCCAUGGGAGACUUGCCGAGGACUUUGUCCACCAAGUGAUGAAAGCAUGCAAAUGCCUCCGAAUCAAAGAUGAGGAAAACAAAAGCUCAGAAACUAUCUUGGAGUCAGCAAGUAAGAAGGAGCUUAGAAAGGCUUAACAUUUUCCAUGCUUCUGCCUGGCUUCAGAGCCCAUGCACUCUGCCUUACCACGGCAGGUGAAAGAUGGCCCCAAAUUCUUAGGUACAUCUCCUGCCAAAAGACCCCUCCUAUGGGUUCUGUGACUACUUCAAUGAAAAGAAUAGGGCAGAAGAGAUGAUGAGAACUUAACAUCUGGCAGUGUCCAUUUCCUGUCUUUUGAAACUUUCUGUUAAAGGCCUGAGCCACGUAUGAAGUGUGAAUCUUCACACCAUGCAAGAGAAGCCACAUGUUAUUGCUCUGGUCAACAAUCCCAGCUGACCCAACCAGAUAGUGUAUCAGGCAUAUGAGUAAAGCAUUCUUAGAUUCUUCAGUCCAGCCCUUCACCAGCAGAACACCAUUCAGCAACCCUUGUCGGCAUCAUGUGGGACAGAAGAACCACCCAGCUGAGCCUUAUCCAAAUUCCUGACCACAAAAUCAUAAGAGAGAAUGACUUCUUUCAUAUCGCUGAAUGGAGCAACAUGUUUGGCCAAGUUCCUGUCCCAGGGAGGAGAACCUUCAGCUUGCAACAAGUCCUGGCCGUUGGAGAAACCAUGAGACUAGACCUUGUGUAAAGCAGCUGAUUCUGCCAUGGGGGAAAUGCCCUUUUGUUUACUGAGCUUCUCCCACCCAUGCCUUGCUCCACUUUCCUCUAGAAGCCUGAGAUAUUGGGAAUAAGAGUCUCAGCCUCCAAGAGAUGGAGAACAUAUCAAGAGAGUCUGGAUUUCUGGGGUGAUUAAGUUCACUUGAUUCAUUAGCCUAAGUGCUCAAGUAAAUUUCAAAUCACAGUGUUAUGUGUGAUUGUCCACGUCCUUCCUCCAAACACUCCCCACCUCCCACCCAAGGGCCCAUGUAACUUGCUAUUGAGAACCUUUGAUUUCUUAGGUAUUUGGGUGAUAGGGUUUUGUUGCCUCUCCUGAAGAAAAUAGUGGCAAUUUGUACUCAGCUGUGGAAUAAAGGAAAUCAUGACAUAAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications