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Homo sapiens (human) microRNA hsa-mir-758 precursor URS000075DEC1_9606

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MIR758: MIR758 is a specific candidate microRNA that has been shown to inhibit the expression or function of ABCA1 [PMC6100038]. Treatment with 1m for 24 h was found to reduce the expression of MIR758, along with other microRNAs such as miR155, miR10b, miR145, miR33, and miR106b [PMC6100038]. Additionally, MIR758 was detected as one of the significantly changed microRNAs in various conditions and diseases such as endometrial, prostate, and breast carcinoma [PMC9866967]. It has also been associated with cell proliferation and differentiation control and neuroblastoma progression [PMC9866967]. Furthermore, in a genomic analysis using the dog reference genome CanFam3.1, MIR758 was found to be one of the strongly differentially expressed microRNAs in a specific region [PMC8376273]. The cluster containing MIR758 also included other microRNAs such as miR134, miR154, miR369, and miR655 [PMC10148110]. Overall, MIR758 is a candidate microRNA that has been implicated in various biological processes and diseases. It is involved in regulating ABCA1 expression or function and has been associated with cell proliferation control and neuroblastoma progression. Additionally, its differential expression has been observed in different conditions using genomic analysis.

Genome locations

Gene Ontology annotations

Sequence

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GCCUGGAUACAUGAGAUGGUUGACCAGAGAGCACACGCUUUAUUUGUGCCGUUUGUGACCUGGUCCACUAACCCUCAGUAUCUAAUGC

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Publications