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Homo sapiens (human) long intergenic non-protein coding RNA 320 (LINC00320) URS000075D792_9606

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LINC00320: LINC00320 is a long non-coding RNA (lncRNA) that has been studied in various contexts, including glioma, ankylosing spondylitis (AS), and osteosarcoma. In glioma, LINC00320 expression was found to be reduced and it was shown to inhibit the proliferation of glioma cells by repressing the Wnt/β-catenin signaling pathway [PMC7436175]. Additionally, LINC00320 was found to suppress tumorigenicity and angiogenesis in glioma by reducing NFKB1-regulated AQP9 [PMC9019982]. In AS patients, LINC00320 was not significantly overexpressed compared to healthy controls [PMC6938967]. In a study on low-grade glioma, LINC00320 was identified as one of the nine immune-associated lncRNAs predictive of the disease [PMC9127066]. Furthermore, LINC00320 has been shown to inhibit angiogenesis by downregulating NFKB1-mediated AQP9 [PMC8595242]. However, no other associations with human disorders were found for LINC00320 except for its involvement in certain types of cancer or genetic diseases [PMC9917164]. Overall, these studies highlight the potential role of LINC00320 as a tumor suppressor in glioma and its involvement in immune-related processes.

Genome locations

Gene Ontology annotations

Sequence

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ACUGUGUGAUUUUUGUUCUUUAGUAGAAGGAUAACAUGACAUAGCAGGAAUAAUACUGCCUUUUCUUUCUGGCAUGGAUCAAGAGAAAAGAAAAUACAAGAAAACAGACAGAAGAUCCUAUCUGCGACAAUUAAGAGCACUCUAAGAGGAAAACACAUCCCACCACACAAGGCAAGGUACUUCUAUGGAAGGGUGAGCCCUCACAGAUGGAGCAAUGGGGCGCGCACACCUGAACAAGGGAGGGGAAGGAGUUCUUAUCCCUGAUGCAUGUGACCCCUGCUGCUGUGUCCUUCCCCUAUUGGCUAAGGCUUCUGACAGCUUUGGAGAUUGUGACAUUGGAAUAAAGGAAAAACGUACAGGACUCAUGAAGCGCUGAAAUGUUCACAAAUAUCAAGCAAAAGUCAAUGAAAUUUAUUUUGAGCUAUUUACAUCAUUUAAUAAUUGAGCAAGGUAUACUCCUAUGAACAAAAUUUGGAGCAUGUUUGUCUCUCUCUGCCUGGCGUCUUCAGAAUUUGGAAACUAGUUAUGGUUUAUAAUCAGCUAUAGAAUUUUAACACGUGCUCUCAAAUGCAAGUUUCUGAUAACUUUGGAGAUUGUGACAUUGGAAUAAAGGAAGAGCUGGAAUGUUCAUGAAUAUCAAGCAAAAGUCAUGGAAAUUUAUUUUGAGCUAUUUACAGCAUUUAAUAAUUGAGCAAGGUAUACUCCUAUGAACAAAAUUUGGAGCAUGUUUGUCUCUCUCUGUCUGCCUGGCAUCUACAGAAUUUGGAAACUAGUUUCGUUCCCAGAUUUCCUAAACUUUCCAGAGAAAAUGGUCUUCUCCCUGGCUCAGCAAGAAGAUGAACUUUAAACACUGAGAAACUGGUCAUCUCCCUGGCUCAACCAGAAGAUGAACUUUAAACACUACUCUCAAUGACUUGAUGUUCCCAUCACUACUCCUGUCAUAAAGGGAGGGGACUCAGAUAUUGAGAAUUUUAUGAUAGUGUGAACUGUCUGGUAUGUCAUUUAAGUAAGCCCGUUGCUGAAAUAUUUUCCAUGUUAUUAGAAAGAGCUGAAGAGAGGGAUUGAGAUGGCUUCUUUAUUUUUUGUCUUUUGGGAAUUAAAGGAACCUGGUUCAACAAGGGCCUACACCUAAGUCUCUUGUUGUACCAGAGUACAAUUUAGGACUGCUCCUGAGGAAGGAAUUAGCUAGAAAUCUAGAGAGUAAGGGUAACAGAUUUACAUAGAAUAACAGCCUCAGUAUUUUUGGUUCCUCUCCAGUAAAGAUCACAAAGAAUAUUGCUAAAUCGCUAAAACACCUUUGCAAUAACGUAAGGGCUUACAACUAUAUACCAAUGUAGCUCAGUUACUAAACUGGAGUAAACUAAUUUCUCUUGUGUAGAAAAAUUGGUUGGCUGUGGUUUUAUAGCAGAUCUGCAAUUAUUAAUAGUUAUGCCAAUAAUCGUUUAACAGUGCAUAUGUUAAUAUAUAUGGAAAGACAAUGUGUAUAGACAGAUGUGUAAAAUUGAAAAAUAAACAUAUAACAAGAGAGAAACAUCUAUCGAACAGACAAUAUACAUACACAUCAAACACAACAGCAGUUUUAGUGACCAUAAUAUUUAUUUCUCAUUUUUACAUUGCUUACUUUAGUGACAACUGAAAAUGACAGUUGGCAAUGCAGCUAACAGUUUCAAUAAAAGUAUAAAACAAAAGACUGUGUACAAAGCACCUGUCUUUCCGCUUUUGUAAUCUUCCGUUGGAAAAAAUUUACACACCUAAGUAACCAUCUGUUUUCUUCAAGAAAAAAUCAUUCUUAUUUCUCUCUCUCAUCUUGAAAACAGCUGUCAGCCAGGAGGGCAGAGCUGAAAUUUAUUGCCACAUCACAUGAAGCAUAGAACAGACUCCACUACUCCUUGAGAUUCAAAACUUUGCCUCUCACAAAGUUACCUUUUAUUUUCCUCUUGUUUGUCACUCAUCUCCCCUAGUGUGCUCUUUUUAUUUCUUUUACUAUUAAUAAUAAAAUCUGUGGAUGACUGUAUUAUU

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Publications