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Homo sapiens (human) hsa-miR-7515 URS000075D66F_9606

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hsa-mir-7515: Hsa-mir-7515 is a miRNA that was found to be upregulated in exosomes in the culture medium of both UVA and UVB groups, according to the results of a qRT-PCR analysis [PMC7719707]. The relative expression of hsa-mir-7515 was analyzed using the 2–ΔΔCt method [PMC7719707]. In collagen vs. control exomiRs, hsa-mir-7515 levels were upregulated [PMC8578291]. Hsa-mir-7515 was also found to be a predicted target gene in type 1 collagen-stimulated cultures, along with hsa-miR-3942-5p and hsa-miR-23a-5p [PMC8578291]. However, the miRNA-gene networks did not connect with each other in this context [PMC8578291]. In a transendothelial electrical resistance (TEER) assay, the mimic of hsa-mir-7515 did not change TEER in SCE cells [PMC8578291]. On the other hand, the mimic of hsa-mir-7515 upregulated VEGFA, VEGFR2, PECAM1, and Tie2 mRNA levels and increased VEGFR2 and Tie2 expression [PMC8578291]. Hsa-mir-7515 is also annotated as part of a two-exon MXE cluster in human transcript annotation along with other genes such as CACNA1E and CACNB2 [PMC6071210].

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Gene Ontology annotations

Sequence

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AGAAGGGAAGAUGGUGAC

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