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Homo sapiens (human) ZNF674 antisense RNA 1 (head to head) (ZNF674-AS1) URS000075D439_9606

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ZNF674-AS1: ZNF674-AS1 is a long non-coding RNA (lncRNA) that has been shown to play a role in regulating apoptosis in cancer cells [PMC9320539]. A study indicated that forced expression of ZNF674-AS1 increased apoptosis in AGS/OXA and MKN-45/OXA cells, as measured by Caspase-3 activity assay [PMC9320539]. Previous research has also demonstrated that ZNF674-AS1 can regulate miR-423-3p, suggesting its involvement in biological processes [PMC8798196]. In another study, the expression levels of various lncRNAs, including ZNF674-AS1, were measured using qRT-PCR after treatment with ivermectin in A2780 and TOV-21G cells [PMC7272521]. The results showed changes in the expression levels of multiple lncRNAs with different concentrations of ivermectin [PMC7272521]. These findings highlight the potential role of ZNF674-AS1 as a regulator of apoptosis and its involvement in cellular responses to different treatments. Further research is needed to fully understand the mechanisms by which ZNF674-AS1 functions and its potential as a therapeutic target for cancer treatment.

Genome locations

Gene Ontology annotations

Sequence

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AAAGCAAUGCGCACGCGCAGUGGCUUUGAAGGCGGGGCAACAAAGCCUGUGGCCGAUGUGGCGCUCCUCGGCCCGCGCUUCAGUGGUUAUGACAGUGUUCGCUCUAAGGGGAGAAGGAAUGUGUGACCAUUUCCAACGGUUAACUUGCAUUCCCCAGAUAGUUUGGAUGAGUUACAACCUAAAUCUGCAAACUCAAUACAGCCAGACCCUGGGAAGUGACUCUCUCCAAGCCUCCUGUACAAGUCCCAGGAAAAGAGCCUGUUUUCCCUUGGACAUGUGAGCAGUGAAUUACUGCUCAUUCAGAAUUUCAUGUGUAUGUGUUACUGAUGGCCAGGUUUAGAGAUACCAACCUAUUUAUUUCUAGAGGAGAGGUGAUUUGAUAACCUUUUCAGAUAUCACUAUCAGUAGGCAGAAAAGGGUUAAUAGUAUGAUAGGGUUAAUAUGUCCUGAGGAGAGUAAAGAAAUUGCAAACUGCAGAAGCACCUGAUCUGUGGCCCUGGCCAGCAUCUCUCCAUAUCCUGAUUCUGUAAGAUCAAGUGUUUAUGCAGAAAGAGAAGGGACUGAUGAUUUGAAUGUGACCAGAUGCAGGGCAUGCCCUUAUUGCCAUGCCAGCAUUUGCUAUUCAUGAUGUUAGUAUUCAAAAAUCAAGAAACACCCUUCCUGGGCCAUUGGUGUCUACUAAUCCAUUGGAAGAAAAGACUGGAAUCCACCACUUACUAGCUUCUUGGGCCUCAGUCCCCUCUUUUCUGCCAUAGCUAAGGACCACCUAACCUAGAUGGCUGUUGUUAUUGUUCAAAGGGACAUCUUUAGAGCCUCAAGCCCAGGAAUAGCCCGUGGCAGGCACCUGGUAAAUGUUAGUUUUCAUUGUCCUAUCCCAACACUAUGAAACAUGCAGCACUCUCUGCAACUGCCCCUGUGGAUUUCCAUAGGCAGGAGAGUAUCCAGUGUUGAGUGGAGCUGGUAUUCUCAGAAACGAAGCCCCUUUCCUCAUUUUGCGCCAAUCUCUUCAGUCAUUUUUACCCUAGUAGUAUAAUGCUUUGUCAAAGUCACUGUCAUCUGAUGUUAACAGUUGUUUUCGCCAGAUGACUUUUCAAAAGGUAACUUCACCAUAAUACCGGUUAAUGUGAUAAAAACACUGCAUGUAGCCAAUUUUUUUUUUUUUUGAGAUGGAGUUAUUGGCUCUUGUUGCCCAGGCUAGAGUGCAGCGGCGUGAUCUUGGCUCACUGCAACCUCCAUCUCGUGGGUUCAGGUAAUUCUCCUGCCUCAGCCUCCCGAGUGGCUGGGAUUACAGGCACACGCCACCAUGCCCAGCUAAUUUUUUUGUAUUUUUAGUAGAGUCGGGGUUUCACUAUAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAGGUGAUCCGCCUGCCUCAGCCUUCCAAAGUGCUGGGGUUACAGGUGUGAGCCACUGCACCCAGCCAAAUAUUUUCUUAUUUAUUUAUUUAUUUUAGAGACAGGAUGCCAUUAUGUUGCCUAGUUUGGAAUGCAGUGUCUAUUUAGAGGCGUGAUCAUGGCAUACUAUAGCCUCGGCUCAAAGGACCCUGGUCUCAAAGGACCCUGCCACCUUAGCCUCCUGAGUAGCUGGGACAAGUGUGCGCCACCACACCUGGCUAAUUUUUUAAAUUUUUUGUAGAGAUAGUGUCUCGCUAUGUUGCCCACGCUGGUCUGGAAUUCCUGGACUCAAGGCCUCUUCCUGCCCUCAGACUUCCAAAGUGUUAGGAUUACAGGGUGAGUCACCACGCCCAGCCAGUGUGAAUUUUCUAAUGCUGAGUAAGUUGUGAUCCAGAAGUAAAUGUAUCUGCAAGCUGAUUUAAAUUGUAGAUUUUCUCUUCAUUGCAUAUUUUCUGAUGUUGAAUAAAGUCUGAGUAUUAACUAAAGUUUUUGCUUCUUAAAUAUGUAAGAAUUGUCCUCAAAAUCUCUAUUCUUGAGCACAGUAGUAAAAAUAUUUUUACAUACAUUGUAUUUCAAGGGUUCUGCAUAAGCAACCUUGUUUUAUUGUGACAAUUUAUUUGGGAAUUGUAUCAAAUAUAUAAUACUGAGAUGUUCUCAUUCCUUUUGUGAAAAUACUUUUGUUUAAAAACCACUGCCUUCAAAUGAAAACCACUAGGUUUGUUAU

Taxonomic tree

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Publications