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hsa-mir-5047: hsa-mir-5047 is a human microRNA (miRNA) that has been identified as a potential target for SARS-CoV-2 [PMC9346380]. It was selected along with hsa-miR-6743-3p and hsa-miR-4745-5p based on their high database scores [PMC9412912]. Additionally, hsa-miR-6776-5p and hsa-miR-4436b-5p, which had the highest scores in individual databases, were also selected [PMC9412912]. These five miRNAs were identified as potential candidates for targeting SARS-CoV-2 sequences [PMC9346380].
Furthermore, hsa-mir-5047 was found to be part of a specific ceRNA (competitive endogenous RNA) network with two other miRNAs (hsa-miR-532–3p and hsa-mir-5047) and four mRNAs (GLU, FOSL2, GALNT6, NOP2) [PMC10034150]. This ceRNA network was formed in conjunction with circGAPVD1 [PMC10034150].
In a separate study, it was found that hsa-mir-5047 is one of the 11 common miRNAs that may target SARS-CoV-2 sequences [PMC7565861]. The other common miRNAs include hsa-miR 1301–3p, hsa-miR 125a–3p, hsa-miR 196a–5p, hsa-miR 19b–2–5p, hsa -mi R4758 -5 p ,hsa -mi R141 -3 p ,hsa -mi R120 2 ,hsa -mi R19b1 -5 p ,hsa -mi R15b -3 p and hsa -mi R153 -5 p [PMC7565861].
Overall, these studies highlight the potential role of hsa-mir-5047 in targeting SARS-CoV-2 and its involvement in ceRNA networks [PMC9412912] [PMC10034150] [PMC7565861].
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