MIR646: MIR646 is a microRNA that has been shown to regulate FGF2 and is also associated with colorectal cancer [PMC4823089]. It has been reported that MIR646 can bind to hsa_circ_0081143 and effectively reverse the inhibition of CDK6, which is related to lymph node metastasis and poor prognosis in gastric carcinoma patients [PMC8335809]. In a study evaluating the prognostic values of different genes, higher expression of MIR646 was associated with better overall survival in patients [PMC9113459]. In pancreatic ductal adenocarcinoma (PDAC), MIR646 is one of the amplified genes that are involved in cell proliferation, tumor growth, metastasis, apoptosis, migration, invasiveness, and epithelial-mesenchymal transition (EMT) [PMC9599555]. Additionally, MIR646 expression was found to be upregulated in a study on patients with systemic-onset juvenile idiopathic arthritis (SoJIA) [PMC9324496]. Overall, MIR646 plays a role in various biological processes and has been implicated in different diseases.