hsa-mir-8073: Hsa-mir-8073 is a miRNA that has been identified as a potential tumor suppressor and serum biomarker for ovarian and pancreatic cancers [PMC9187062]. It was selected as one of the 10 PRNP-related miRNAs in a screening study [PMC10047351]. In cancer diagnosis, hsa-mir-8073 was found to be one of the five balanced miRNAs selected by random forest models [PMC9187062]. In a combined model for cancer screening, hsa-mir-8073 was one of the four miRNAs that achieved the highest AUC value [PMC9187062]. The function of hsa-mir-8073 in cancer diagnosis is supported by its interactions with other miRNAs, as shown in Figure 4O, J, 4H, 4G, 4D, 4E, and 4A [PMC8942883]. In a study comparing plasma-microRNA levels between affected and unaffected individuals, hsa-mir-8073 was found to be down-regulated in the affected group [PMC6114494]. Additionally, hsa-mir-8073 has been identified as having a great contribution to gastric cancer prediction [PMC8785967]. Overall, hsa-mir-8073 is an important miRNA with potential roles in tumor suppression and cancer diagnosis. It has been shown to be down-regulated in certain cancers and may serve as a valuable biomarker. Further research is needed to fully understand its mechanisms and potential clinical applications.