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hsa-mir-1288: Hsa-mir-1288 is an upregulated microRNA (miRNA) that has been found to be differentially expressed in various conditions, including ectopic pregnancy (EP) and colorectal cancer [PMC5959728] [PMC7183093] [PMC5952075] [PMC5352919] [PMC5223123]. In EP, hsa-mir-1288 is upregulated compared to normal pregnancies, along with hsa-mir-451 and hsa-mir-223, while hsa-mir-196b, hsa-mir-30a, hsa-mir-873, and hsa-mir-337-3p are downregulated [PMC5959728] [PMC7183093]. Similarly, in colorectal cancer, hsa-mir-1288 is also upregulated and associated with disease progression [PMC5223123]. In addition to EP and colorectal cancer, hsa-mir-1288 has been found to be differentially expressed in other conditions as well. For example, it is upregulated in L02/HBx cells and associated with hepatocellular carcinoma progression [PMC5352919]. Furthermore, it has been identified as one of the differentially expressed miRNAs in ovarian tissues compared to other tissues such as liver and testis [PMC5223123]. Overall, the dysregulation of hsa-mir-1288 suggests its potential role as a biomarker or therapeutic target in various diseases.
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