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hsa-mir-146b: Additionally, miRNA hsa-mir-146b is highly expressed in PB NK cells, and its target TRAF6 has been reported to down-regulate NF-kB activity, suppress cell proliferation, and enhance chemosensitivity [PMC3640206]. The expression, log2 fold change, and adjusted p-value of hsa-mir-146b, hsa-miR-375, hsa-miR-31, hsa-miR-7-2, and hsa-miR-204 were then extracted from the overall results [PMC4918724].
MIR146B: MIR146B is a gene that can be targeted using the "PAM-out" strategy, where the PAM sequences are oriented towards the 3' region of the target DNA sequence [PMC8348963]. In a study, it was found that the expression of Th17-related microRNA (miR-155) and inflammasome-related molecules (AIM-2, Mincle, and NLRP3) was increased in response to an Aa challenge in the aorta [PMC4665422].
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