hsa-mir-653: Hsa-mir-653 is a microRNA that has been found to have low concentrations and is difficult to analyze [PMC3942699]. However, it has been identified as a potential target in several studies related to Alzheimer's disease (AD) [PMC9312389]. In addition, hsa-mir-653 has been shown to have a higher degree of interaction in a network analysis [PMC7510080]. It is speculated that hsa-mir-653 may play important roles in the biological behavior of EC (esophageal cancer) through multiple pathways [PMC7510080]. There are limited reports on the role of hsa-mir-653 in the malignant biological behavior of tumors [PMC7510080]. Hsa-mir-653 has also been identified as one of the miRNAs involved in child obesity traits [PMC9092671]. It has one functional binding site with hsa_circ_0003258 [PMC8599237]. Furthermore, hsa-mir-653 has potential target genes identified from various databases and is associated with poor prognosis in stomach adenocarcinoma (STAD) and lung cancer [PMC7423976] [PMC6856753] [PMC9322918]. In pancreatic ductal adenocarcinoma (PDAC), hsa-mir-653 expression levels were found to be different between tumor tissues and adjacent normal controls, with upregulation observed in PDAC tissues [PMC5649611].