Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) C21orf91 overlapping transcript 1 (C21orf91-OT1) URS000075C022_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

C21orf91-OT1: C21orf91-OT1 is a long non-coding RNA (lncRNA) that has been found to be involved in functional processes of the immune response [PMC7993680]. It has been significantly increased in cases of foetal growth restriction, although there is currently no published evidence linking it to cancer [PMC7993680]. In a study, it was identified that C21orf91-OT1, along with other lncRNAs such as LOC105375787, CYTOR, URB1-AS1, CASC15, LOC101928433, FLJ45139, and HOTAIR acted as oncogenes [PMC7993680]. Furthermore, the expression levels of CASC15, FLJ45139, LOC101928433 and C21orf91-OT1 were found to be significantly increased in bladder cancer tissues compared to adjacent tissues or normal mucosas [PMC7993680]. Higher expression levels of these genes were associated with shorter survival in patients [PMC7993680]. Patients with higher risk scores were more likely to have higher expression levels of risk-related lncRNAs including C21orf91-OT1 [PMC7993680]. Additionally, C21orf91-OT1 was found to interact with more than 6 miRNAs along with other lncRNAs such as NEAT1 and small nucleolar RNA host gene 3 [PMC7003033]. In terms of tissue expression patterns according to GTEx release version 6 data, C21orf91-OT1 showed the highest median expression in testis followed by whole blood [PMC9844503]. Finally, a prognostic model was constructed using the expression levels of various lncRNAs including C21orf91-OT1 for bladder cancer prognosis prediction [PMC7993680].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences
GCUGUGAAAUUGUUCUGUCUUUGAAAAAAAAAAUGUUUGGAUGGCACAAGUCACCACCUCUAGAAGCAAAAACUUCAACCUCCUGUGUAUCUGAGGCACCUCGCCCUGACUGGUAAAGCAAAGAAACUGGAUAGGAGAAGGCCUGUGUUGAGGGCAUCAAUGGCUAACUGUCAGCAGGGACAACAGCCAUUAUCCCAUAUCCAGUGAGUACAACAGACUUGCUGCAGUUUUACAUCCAGUUCACUGAUCAACUAUCAAACUGAAGGAUAGCUUGUCACUGCAUCUGCAGUGACUCACUUGCCUUGGGGAAAAAUACAUGUCACACAUUUACAUUUUGGCUUUUAAGUGAGGAAACUUCAUGGUUUUCAGAACAGAGUAAGAUUCUUGAAAACUAAAACAAUAAAUCCAAUGCUGAUUGUGAUCAAUGAUGAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications