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Homo sapiens (human) microRNA hsa-mir-623 precursor secondary structure diagram

Homo sapiens (human) microRNA hsa-mir-623 precursor URS000075BF27_9606

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hsa-mir-623: Hsa-mir-623 is a microRNA that has been found to inhibit the phosphorylation of ERK, although the exact mechanism is still unknown [PMC6561617]. The results of a study suggest that hsa-mir-623 may downregulate MMP1 expression both directly through post-transcriptional degradation and indirectly through transcriptional inhibition [PMC6561617]. In addition to hsa-mir-623, several other microRNAs have been identified as potentially involved in this process, including hsa-mir-1178, hsa-mir-1276, hsa-mir-197, hsa-mir-217, hsa-mir-485-3p, hsa-mir-502-5p, hsa-mir-526b, hsa-mir-532-3p, hsa-mir-554, hsa-mir580 ,hsa -mir -583 ,hsa -mir -610 and has -mir -942 [PMC6794874]. Further investigation is needed to fully understand the role of these microRNAs in regulating MMP1 expression and the specific mechanisms involved [PMC6794874]. The findings suggest that these microRNAs may have potential as therapeutic targets for controlling MMP1 expression and potentially influencing related cellular processes [PMC6794874]. However, more research is required to validate these findings and explore their clinical implications [PMC6794874].

Genome locations

Gene Ontology annotations

Sequence

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GUACACAGUAGAAGCAUCCCUUGCAGGGGCUGUUGGGUUGCAUCCUAAGCUGUGCUGGAGCUUCCCGAUGUACUCUGUAGAUGUCUUUGCACCUUCUG

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2D structure Publications