hsa-mir-614: Hsa-mir-614 is a microRNA that is involved in various biological processes. It has been found to have fixed substitutions in two miRNAs, including hsa-mir-614, indicating genetic variation [PMC4841587]. In a study on progesterone support, hsa-mir-614 was found to be overexpressed in the group receiving progesterone alone [PMC3462109]. Additionally, hsa-mir-614 was identified as one of the miRNAs sequestered by circRNA_089763 [PMC6691254]. Hsa-mir-614 has also been implicated in various pathways such as fatty acid metabolism and biosynthesis, mucin type O-Glycan biosynthesis, and TGF-beta signaling [PMC7555983]. In the context of multiple sclerosis, hsa-mir-614 was identified as part of module #451 [PMC9618768]. Target genes of hsa-mir-614 include MAPK1 and RHOT1 [PMC6462295]. The expression levels of hsa-miR-6726-5p, hsa-miR-7111-5p, hsa-miR-1247-3p, and hsa-mir-614 were used as input variables in a computational analysis [PMC6462295]. References: [PMC4841587] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841587/ [PMC3462109] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462109/ [PMC6691254] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691254/ [PMC7555983] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555983/ [PMC9618768] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618768/ [PMC6462295] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462295/

MIR614: MIR614 is a microRNA that is expressed at elevated levels in AA-TNBC tumors [PMC7801944]. The increased expression of MIR614 in AA-TNBC tumors suggests that it may play a role in cell migration and invasion [PMC7801944]. However, it was found that MIR614 does not increase the expression of ΔNp63, a protein involved in cell proliferation and differentiation [PMC7801944]. These findings indicate the need for further investigation into the specific mechanisms by which MIR614 contributes to cell migration and invasion in AA-TNBC tumors [PMC7801944]. Understanding these mechanisms could potentially lead to the development of targeted therapies for this aggressive form of breast cancer [PMC7801944].