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Homo sapiens (human) FLVCR1 divergent transcript (FLVCR1-DT) URS000075BC20_9606

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FLVCR1-DT: FLVCR1-DT is a favorable long non-coding RNA (lncRNA) that has been utilized for monitoring the prognosis prediction of pancreatic cancer (PC) patients [PMC9124146]. It is one of the autophagy-related lncRNAs found to be involved in cancer prognosis, specifically in PC [PMC9124146]. In PC, FLVCR1-DT has been identified as a protective factor associated with longer overall survival [PMC8188897]. It is part of a risk score formula that includes other lncRNAs and is used to predict prognosis in PC patients [PMC8188897]. FLVCR1-DT has also been implicated in the severity of COVID-19 infection, with higher expression levels observed in patients with moderate and severe infection compared to controls [PMC9687826]. In COVID-19 patients, FLVCR1-DT is associated with complications and mechanical ventilation as indicators of disease severity [PMC9687826]. Additionally, FLVCR1-DT shows a significant positive correlation with IL6 levels in COVID-19 patients [PMC9687826]. The expression levels of FLVCR1-DT are deregulated in COVID-19 patients, showing a significant increase compared to controls [PMC9687826]. In summary, FLVCR1-DT is an autophagy-related lncRNA that plays a protective role in PC prognosis and is associated with disease severity and complications in COVID-19 infection.

Genome locations

Gene Ontology annotations

Sequence

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GAGAACUUCGGGAGGCGGGGGAGGAAAGCGGCCGGCGAGCGCUGGCUGACAUUUUCCUGCCCGGAAGGAUGCAUGGCCCGGGGUCUCCUGCACCUGAGGGUGGGCGGGAGGCGGCCCCGCGGGUUGUGUUGCUGGAAAAAGGGGUCUCGAUCCAGACCCCAAGAGAGGGUUCUUGGGUCUACUUCAGGGAAGAAUUGGAGGCGAGUCACAGAGCGCAGUGAAGGAAGCAAGUUUAUUGGAAUCUACUCCGUUAGAGAGUGCAAGUCCUCAGACUGCAGGAGGAGGAACUCCCGUCCUUCGGUAGUGUCACUACUUAGAGGCAGCUGUGAGGAGCUGUGAUUAAUCGUGGAAUGUGCUGAUGUGCCCACUAAAGAUGCCUGGUAAGCAGUGGCUCCUCUAACAAGUGGGCAGCUUGGAACUGGGAACGAGAGAGCCACCGAAACAGAAUGAGGGAGACAAAGAAGUGGGCAUCACCCUUAACUCCACAAGGGCUUCCCAAGGGCGCUGUACCGUACGCAGGCCCAGGACGAACUUUAUUUCUCGCCCCAGCAUCGCUGUCCUUGUCGGUGAGACCCUGGCUUUAGGGCAGACAGGACCACGUUUCAUAAGUUCAUGCUGUCCCAGCAGAGGAAUAACGCCAGAAAGUGUUCCAGUACAACCAGAGAAAGAGAGUCCAUGAGAAAUCUGCCCUUGUGAAGUUGGAAUCCCCUCAACCUCACCCCGCUGACUUGAAUGAAGCGACUGAGACGGGCUAUGAUGGAGCAGAUCCGGUUGCUCGACCUUCUCCCUUGCACCAACACAUGUAGUUAAUAGUUACUGGACAUGCAUAUUCAGUGGGUUCCAGGUACCAAACUUGUAUUGAAUGGUAUGUGCCAGACACCGUCUUGAGAUCUGGAGAAUAAAAAAAUAAAAAAAUAAAAACGAGACAUCCAGAGCACAGUA

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Publications