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Homo sapiens (human) long intergenic non-protein coding RNA 629 (LINC00629) URS000075BA7E_9606

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LINC00629: LINC00629, a long non-coding RNA (lncRNA), is highly expressed in reproductive tissues such as the ovary, cervix, and placenta [PMC4833476]. MiRNAs flanking the same region as LINC00629 also exhibit higher expression in these reproductive tissues [PMC4833476]. In response to apigenin treatment, the protein level of Mcl1 is significantly reduced, and this reduction is reversed when LINC00629 is knocked down [PMC9740369]. Knockdown of LINC00629 has been shown to significantly suppress tumor formation, resulting in reduced tumor weights and sizes [PMC9764730]. Furthermore, knockdown of LINC00629 in MNNG/HOS cells treated with TM (thapsigargin) leads to a decrease in the ubiquitination of KLF4, suggesting that LINC00629 affects the polyubiquitination of KLF4 under ER stress [PMC9764730].

Genome locations

Gene Ontology annotations

Sequence

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UGCCGGGACGGCGCAAGGUGGCUGAGCGAAGCUUUUUGCUCGGUGCUUACAGGGAGUACCUGAGAUGGUUUGGGAAAGGAAACAGGGGGUCUCAGACCGCUUGGGUGCAGCGCUCUCCCCAUGCGUUUGAGUGCAGAUCUGUCGAGACGCCCCAGCCCUCGCCACCCCACCAAGCUCUCAGGUAGAGAGGCCCCGGGACAGGAAACCUGUUUAUGCACCCUCCUGCAAUCCCACCACCUGCCCAGGCCAAGUGAGCCCCUCUCCGCUACUGGUGUUUCAUAAUGCUGGGAGCUACUUUGAUUUCAUGCAUUGCCCUUCAGCUGCCAUGUUAUGAGGACACUUGGAGAAAGCUACAGGAGAGGAACUGAGGUCUCCUGCCAUCAGCCACUUGAGUGAGCAUGGGAGUGGAUUCUCCAAACUCCAGUUAAGACUUGAGAUGUCCACAGUGGCAGCCACUAGCUUGACUGCAACUUACGAGAGACCCUGAGCCAGAGGCACUCAGUUAAGUCAUACACAGUUUCCUGACCCGUAAAACCUGUGACACAAUGAAGGUUUGUUGUUUUGGGGGUAAUCCGUUAUUCAGCAAUAGAUAACGAAUACAGAAGGCUUGUAAUUGUAUAACCAACGUGAGUUUAUAAGCGGAUAUCUGACCUCAUUUGUUUUCUCCUGAAAAAGUUAUAGAAAAAUCACAAGACUGCAAGUCACUCUCUCUCUUUCUUUUGUGGGGAAUAAACAAGUAUAAUUACAAUUUCUAAACCUAUUGUUUUAUUCUCAAAUAUAAUUACAAUUUAAACAGGAUAUUGUAGAGCUCCAUCAUAGGGAUUAACACUAAUUAGAAUUAAAGAACGUUUUUGUGAAAGUCAGCUUUUUUUUUUUAAAUAAACACUCGUCCCUUGAUAAUGUAUUUCUUUUUCAUAAAAUUAAAAAAAAAAUGUGGGUUGUAGUAGGUGUAUAUAUUUAUGUGGUACAUGAGAUGUUUUGAUACAGGCAUGACGUGUAAUAAUCACAUCAUGGAAGAUGGCGUAUCCAUCCCCUCAAGCAUUUAUCCUUUGUGUUACAAACAAUCCAGUUACACUCUUUUUGUUAUUUAAAAAUGUACAAUUAAAUUAUUAUUGGCUAUAGUCACCCUGUUGUGCUAUCAAAUAUUAGGUCUUAUUCAUUCAUUUAACUAUUUUUUUGUACCUAUUUAUCAUCCCCAUCCCCGGUUCCCUCCCACCACCCACCCCACUACCCUUCCCGGCCUCUGGUAACCAUCCUUCUACUCUCUAGCUCCAUGAGCUCCAUUGUUUUGAUUUUUAGCUCCCACAAAUAAAUGAGAACAUGUAAUGUUUGC

Taxonomic tree

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Publications