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hsa-mir-4295: Hsa-mir-4295 is a microRNA that has been extensively studied in various contexts. It has been cloned into the pmR-ZsGreen1 Vector using BglII and KpnI restriction endonucleases [PMC5302933]. In a study investigating differentially expressed genes (DEGs), hsa-mir-4295 was identified as one of the top 10 microRNAs associated with DEGs [PMC9793038]. In another study, upregulated miRNAs targeting genes involved in cellular senescence and apoptosis, such as SOD3, TNF, BAX, and FOXO3, were found. Conversely, downregulated miRNAs targeting genes associated with anti-oxidation and clearance of intracellular waste, such as ATG12, BECN1, RELA, and MAPK1 were identified [PMC9781133]. Hsa-mir-4295 was also found to be one of the miRNAs involved in a miRNA-mRNA targeted network that had targeted relationships with hub genes [PMC8194198]. Furthermore, hsa-mir-4295 was identified as a potential core microRNA that plays an important role in the development and prognosis of breast cancer [PMC8194198]. Additionally, hsa-mir-4295 has been shown to have a high binding affinity with the SARS-CoV-2 coding region NSP2 [PMC9773347]. It has also been found to have high genomic coverage [PMC9773347] and a negative binding affinity score indicating high binding efficacy [PMC9773347].
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Gene Ontology annotations
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