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Homo sapiens (human) MIR4300 host gene (MIR4300HG) URS000075B57A_9606

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MIR4300HG: MIR4300HG is a long non-coding RNA (lncRNA) gene that has been studied in relation to various conditions, including adolescent idiopathic scoliosis (AIS) and postoperative nausea and vomiting (PONV) [PMC9180299] [PMC7491086]. Studies have shown that a functional variant, rs35333564, located in MIR4300HG is associated with the progression of AIS in both Japanese and Chinese populations [PMC8117547]. Methylation of MIR4300HG has also been linked to the progression of AIS [PMC7309379]. Additionally, MIR4300HG has been associated with reduced incidence of PONV in Japanese patients [PMC7491086]. The gene may regulate the development of PONV through the estrogen signaling pathway [PMC7491086]. Furthermore, MIR4300HG has been found to be associated with scoliosis curve progression and may influence spinal curves during the adolescent growth period [PMC8117547]. However, the biological function of MIR4300HG remains largely unknown [PMC7491086] and further studies are needed to fully understand its role in these conditions.

Genome locations

Gene Ontology annotations

Sequence

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GCCCGUGCCUCUCCCUCCACACCUCCCCGCAACUGAGGGAGCCGGCUCCGGCCUCGGCCAGCCCAGAAAGGGGCUCACACAGUGCAGGGCCGGGCUGAAGGGCUCCUUAAGGGCGGCCAGAGUUGGCGCCAAGGCUGAGGAGGUGCCCAGAGCGAGCGAGGGCUGCCAGGGCUGCUAGCAGGCUGUCACCUCUCAAUAGCAGUUUUGUAUAUGGGAUCUAGCCCCUCCCUAAGAGGUUGAUUCUAAGGAAGCCAACAGCCGUGUUGUGAGUACCCAAUGGAAAGUCUGUUGUGGCAGAAAACUGAUGUCUCCAGCCAACAGCACUGAGGCCCUGAGACCUGCCAACUGUCAUGAUCUUCCGAUGCCUGGACACAGAAAGAGCAGUGGAAGGGGUCGUUGCAUGAGCAAAGACAAAGAGUGGGACACUGACUGUUACAUCUCAAGGAGAAGGAUUGCCAGAUCAAAAGUCUUGCAGUUAACCAGGCGUGGUGGCAGAUACCUGUAAUCCCAGCUAUUCGGGAGGCUGAGGCAGGAGAAUCGCUUGUACCCGGGAGGCAGAGGUUGCAGUGAGCUGAGACCGCGCCAUUGACUCCUGCCUGAUGACAAGAGAGAAUCUACGUCUCAACAACAACAACACGCUUGGGCACUGUAUUAACUCCAUAAUCGGUUUAUUCAUAAUGCUGCAUCAUCCAACCAUCAUCCAACCUAUUUAUCAUUCACAAUGCCACCUGUGAAUACUGGCUUCCAUUGACUCUUUCAAGAAUUGCUACUGGGCCUCACCAAUGUUGACCACAAAUGCAAGUCAUACUGAGAGCCUCUGUGCUCUUUCCCCUGUGGACAAUAACUACCAUUUCAUCCUGGACACCCAUUGUUUGCCUGGACCACACCUUGUUAUGACCAUAACCCUCAGUCAGACUCAACCUUCCUUCAAGAUCUGCAGAUCUAAAUUUUAUUGGGAACAGCUAGUUUGACAAGCAUAGACCAGAUGUCCAGUUGUCAUUCAUUCAGCAGGAGCAGCAAGAUUCAAUCAUGUUUUUAUUAUAUUAUUUCCUGAAACUUGUGGCUGUAACAAUGAAGUUUGAGGAUUGGUCUGUGUAAGUAUGGCAGAAGUGAUGUUAAGUCGCUUAUGAGAUUAGGGUAUAAAAGACUAAGGCUUCCAUGCUUCCAUCUUGGUCUCUGUCUCUCAGAGAACAGUCAUGUGAAUGAUUCUUCUUGAAAGUAAAUCUUCCAGCCCCAGUCCAGUAUUCAAAUGAUCCAGCAACAUUGCAACUUAUGAGAGACCUUGAGCCAUCCAGGUAACAUGCUUCCAAAUCCUGACCCUUAAAACCUGUAAAAUAAUAAAUGUGGUUUUAAACUCUUAAGUAAUUUGUUACAUAGUAAUAAAUAGCUAAUACACCGUC

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Publications