hsa-mir-1257: Hsa-mir-1257 is a microRNA that has been found to be downregulated in HIV-infected breast milk compared to uninfected milk [PMC7395778]. It is also included in the hsa_circ_0000497 ceRNA network, along with other miRNAs and mRNAs [PMC9092689]. Hsa-mir-1257, along with hsa-miR-100-3p, has been implicated in the anti-colorectal cancer (CRC) mechanism of GA-Me [PMC9093067]. These miRNAs were found to be expressed at significantly lower levels in CRC tissues compared to normal tissues [PMC9093067]. Hsa-mir-1257 is also one of the differentially expressed miRNAs in heart failure (HF) and cognitive impairment, along with other miRNAs such as hsa-miR-342-3p and hsa-miR-1246 [PMC8478533]. In a study on CAP-treated cells, hsa-mir-1257 was found to be downregulated [PMC8851033]. Additionally, hsa-mir-1257 has been predicted to pair with hsa_circ_0003829 along with other miRNAs such as hsa-miR-145 and hsa-miR-198 [PMC7545778]. References: [PMC7395778] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395778/ [PMC9092689] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092689/ [PMC9093067] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093067/ [PMC8478533] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478533/ [PMC8851033] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851033/ [PMC7545778] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545778/