hsa-mir-4329: Hsa-mir-4329 is a differentially expressed miRNA in primary open-angle glaucoma (PEXG) [PMC10000531]. In a study comparing the expression levels of miRNAs in PEXG, hsa-mir-4329 showed a mean increase of 20.05% in PEXG compared to the control group [PMC10000531]. Furthermore, hsa-mir-4329 is involved in the regulation of genes related to protein metabolism, such as "protein complex" and "cytoplasmic sequestering of protein" [PMC10000531]. Ten miRNAs were downregulated in PEXG, while ten miRNAs were upregulated, including hsa-mir-4329 [PMC10000531]. Hsa-mir-4329 shares a seed sequence with known Homo sapiens miRNA hsa-miR-4329 [PMC4433274]. In addition, hsa-mir-4329 targets MYH9 and is one of 116 miRNAs that target this gene [PMC10000531]. MYH9 is associated with primary open-angle glaucoma [PMC9967176]. The expression and prognosis of hsa-mir-4329 are also associated with the risk of cardiovascular diseases [PMC9967176].