v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) lysosome cell death regulator (LCDR) URS000075B044_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LCDR: The protein contains a large low complexity disordered region (LCDR) with several positively charged lysine residues which are required for biochemical chromatin compaction in vitro and axial patterning in vivo [Grau et al, 2011; Lau et al, 2017] [PMC7327501]. Moreover, either LCDR or hnRNP K OE significantly increased the activity of the LAPTM5 3′ UTR reporter and failed to change the activity of the mutated LAPTM5 3′ UTR reporter (Fig [PMC8812561]. These findings suggest that both LCDR and hnRNP K play a role in regulating LAPTM5 expression through its 3′ UTR [PMC8812561].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
UGAUGCGGGCUUCGUGAGGCGGAAGUGACGCAGUGUUGUCGUCUCGUAGGCUUGAAAGGUAGGUGCCCGACAUUAGGGACUGUCGCAGCCCGGGGAAUUGUCCCCAUCUGCUGGCUUACCUUGUGGGCGUGGAUCCCCUCUAACUUUCCUAAUUCCCGGGCGGCCCGCGGGCCUGCGGCAGAUUCAGCUCUCAGGACUCCACUUUCAGUUUCUUCCACUUCUGGGGCAGGCUGCUUGUCCUGCCACUCUCAGGCCCCCCACCAGACACGGCAGCAACAGCUGUUCCUAAGUGUUCAACUCGCUCCUUCCCGCAAAUGUAGAAGCUCAAAUCCCUAUAGCAAAUUCCAUAUUCUAUGUCAUUCUUAAUGCUUCCGUCUCUCUGGUUGAAUCUAGAUUGGAUACAAUCAGUGAUGCACAUUUACCAGACAGAGGAUGUGCAGCGUUUACUGUUGAUUUCUCUCUUUUCCUCCCUAUCACCUCAGUUUAGUUCCAGGAUCCACACUCCUCCACCAUAGUCAGGAGAUUCAGGGAAAGUUGGCAGGGUUCAGCUUUCAAGUUGACCCUUGAUGAACCAUGGUCAAUCCUGUUAAGAGGCGUGAAAGCCAAUCCCAGCCAAUGAGACUGGGGAGAAAUCACUGAAGAACUUGUGGAAAACAGACCCUCUGGAUAAAAGACACGUGUGGGGAAAAAGGGGCUUUUUAAUGUUAUUCUGGAUGUUUCCCAAAAGUACUGCUGCUGCCUUGCCUCCCUGACAGACACUGGCCUUAGGAUGACAUGCGGCAGGAAGGAAGGACGGAUCUGGGGUUUUUCAAGACUCACUGAGAUGCACAAGGAACCAACCCUCAAGUAGCCAACUCGUUCCUGUUUGCAUGUGUCGACUGAAAAGAAUCAAAAUAAACAAAAUAUAACUAUUUCUAAGAGGUUACAACUUGCAGGCAGGAAGCAGGCCUCUACCUGAGGCCAUAAAGCAUACUUUGAAGGAGAAAAGGUAGGUAUUUAUGCUAGGUGGAGAGGUAGGAUAUACGUAUUCUGUAGCAUACAGGAGAAGCCUAUGAAAAUUCAUGGAGGAAACUCGUUAGAGACACGCACUGGGCUUACAUAUGAAGAAUAUCCAAAAGCGGAUGACCUGUGUUCACUCUGGGGUGAAGAUUUAACAUUUAAAUGUAUUAUAAUUAGGCUGUAAAUGCAAAAAGGUGAAACAUAGGGCACAAGUUCACGAUCUGUGCAAUCUCCAGAGACCAGUCUGAUCUAGCCUGCAGCUGGCAGUCAUCUGUCAAGAAGGGGCUCUUUGUAGCCCAGAGUAGCUGUCAGGUUGGAACCAUAAAACCAAAAGGAGGGCAUCGGCGGUUAGGUGAAGAAAAGAAGUCUUUUGGCCUUUUUUCCUCUUCAAGUCAGCUUUUGAUAAGAUCUAGUAAUAAUAAGGGGAUGGGUGUGGCUGCAGGUGGGACAUGUCGGUUCUCUGUCCUGUCACAGCUAAGAACUAAGAACUUUAGAGUCUUUCAGCCAUAGAGGGUCCUGUCAUCCAUUGAAGGGAUCAGUCCAUUGGGAUUUUGCCAGUUUUAGCAUUGAUGCUGUGUCCUGGGAAACCCCUGAAUACUUAUCAUAGCAGAAGUUCAGCCACUGUAGCCCUACCUCAGGACCGCUUUUAUGGGAAAGAAUAAUUCCUUUAACUGCUUGAGCCAUUUGAGUUGUGGCUGCUUUUGGUACUUGUAAUAAAUUGAAAGCAUCUUGAAUGUUCUGGGACAGUAAAAGAAUGUGCCUUUGUUUCUGACAGCAAUUAUAAAAUCAAUUAUAUGUUUAUAUUCUAAAAAAUGUUUUGAGUAAUGCUGACAUCAUUGGAAAAGUGCAUCACUUAGAAAAUGUAUCUGUGUGUCAAUUUUGUUUGUUCAAAAUCAGUUUCAUUAAUUUGUGGGAAGAUACACCUUGUACAUUUUACCUAAUUAAAAAAAAUAUUGCCAGUUGAGUAUACUUGUGAUAUAUUCAAAGAUAAAUAAACUUUUUCAAUUUUAGAUAUUCAAAAAAAAAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications