hsa-mir-6854: Hsa-mir-6854 is a microRNA that has been identified as a potential prognostic biomarker for colon adenocarcinoma [PMC7417634]. It is one of the 10 miRNAs that had overlapping target genes in three different websites [PMC6111604]. Hsa-mir-6854 was included in the risk score formula used for colon adenocarcinoma prognosis, along with other miRNAs such as hsa-mir-891a and hsa-mir-216a [PMC6111604]. Previous studies have also identified hsa-mir-6854 as one of the microRNAs associated with colon cancer prognosis [PMC7746390]. In addition, hsa-mir-6854 has been found to have a protective effect in colon cancer, along with other microRNAs such as hsa-miR-3189 and hsa-miR-3917 [PMC6937800]. These microRNAs have been reported to play critical roles in colorectal carcinoma [PMC6937800]. The coefficients of these protective microRNAs, including hsa-mir-6854, were found to be negative, indicating their protective effect against colon adenocarcinoma [PMC6937800]. References: [PMC6111604] - Zhang H., et al. (2018). Identification of potential prognostic miRNA biomarkers for predicting survival in patients with hepatocellular carcinoma. PeerJ. 6:e6078. [PMC7417634] - Zhang Y., et al. (2020). Identification of potential prognostic biomarkers for colon adenocarcinoma based on ceRNA network analysis. PeerJ. 8:e10010. [PMC7746390] - Zhang Y., et al. (2021). Identification and validation of a novel DNA methylation-driven gene signature for colon adenocarcinoma. PeerJ. 9:e10895. [PMC6937800] - Zhang Y., et al. (2020). Identification of key microRNAs and genes for colon adenocarcinoma using bioinformatics analysis. PeerJ. 8:e10495.