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Rattus norvegicus (Norway rat) rno-miR-6321 URS000075AB45_10116

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rno-mir-6321: Rno-mir-6321, a microRNA, has been extensively studied in the context of DMED (diabetic microvascular endothelial dysfunction) [PMC9482859]. A study predicted that rno-mir-6321 targets 98 genes [PMC9482859]. In DMED, the expression of rno-mir-6321 was found to be upregulated, along with rno-miR-122-5p, following intervention with MSCs (mesenchymal stem cells) [PMC9482859]. Furthermore, rno-mir-6321 was found to be upregulated in DMED rat samples [PMC9482859]. Additionally, it has been identified that rno-mir-6321 is one of the miRNAs sponged by the circRNA 014900 [PMC6939336]. The circRNA 014900 has binding sites for multiple miRNAs, including rno-miR-466b-5p, rno-miR-6332, and rno-mir-6321 [PMC6939336]. References: [PMC9482859] - Liang Y et al. (2020) Mesenchymal stem cells attenuate diabetic microvascular endothelial dysfunction through modulation of exosome-associated miRNAs directly targeting RhoA/ROCK signaling pathway. Aging (Albany NY) 12(2):1707–1724. [PMC6939336] - Wang Y et al. (2019) Circular RNA circ_0149003 promotes high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells via miR-466b-5p/CTNNB1 and miR-6332/CTNNB1 pathways. Sci Rep 9(1):9353.

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Gene Ontology annotations

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UACUGCAGUGAGUUCUAUGAAGC

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