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Homo sapiens (human) long intergenic non-protein coding RNA 887 (LINC00887) URS000075A9B0_9606

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LINC00887: LINC00887 is a long non-coding RNA (lncRNA) that has been studied in various cancer types, including esophageal cancer, renal cell carcinoma (RCC), and lung cancer. In esophageal cancer, the relationship between LINC00887 and miR-454-3p was verified using dual fluorescein reporter gene and pull-down assay [PMC7792119]. Somatic copy number variation analyses revealed that LINC00887 is involved in lncRNA dysregulation in esophageal cancer tissues [PMC6089161]. In RCC, knockdown of LINC00887 significantly suppressed cell proliferation abilities [PMC7459398]. Additionally, the serum LINC00887 signature showed potential as a diagnostic marker for RCC patients [PMC7459398]. In lung cancer, a decrease in LINC00887 was suggested as a prognostic and diagnostic marker [PMC7751375]. However, the detailed regulatory mechanism of LINC00887 in regulating the immune response in clear cell renal cell carcinoma (ccRCC) remains to be determined [PMC9436564]. Overall, these studies highlight the potential importance of LINC00887 as a biomarker and therapeutic target in various types of cancer. Further research is needed to fully understand its regulatory mechanisms and clinical implications.

Genome locations

Gene Ontology annotations

Sequence

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AUUCAUUUUCUGCUCAGACACCGUUGCUUGCAAAAUUCCACCCAGAAGAUAAGGGAGGGAGUAUCGCUGCAGCGUCCUGCUCUGUGCCUGGUUAUAUUACUGGAUCCUUGUGUUGCAGCCCUAAGAUAGAAGGAUUGUCUCCAUUUCACAGAUGAGAGAGAACUGAUGCGCAGGAGGCUGAAAUUGUCUGAAGUCACACAGCAGCCUCCUCUUAAACAUGACAAAGAAUCCAAGGACUUGUGCUGGGGCUGUCAGCUGCUAUUCUGGUGCCCUGGGGACGAAGAAGGGAUCUGGAGGGAAGACUGUCACCCUCUUGCGAAUGUUUCCAAGAAGCAGCUCAGCAUGGGAGAGAAAAGGGGAGAUCCCAGUUCCAGGAACACCUGGCCAGUGUUUCACCUGUUUAUCGGAGUUGACAGGACCAGCCAGCCCUUUCCCACCUCUCCCCAUCAUGAUGGAUGGGAGCCUGGCCUUUGAGAUUCCUGCGAAGGAAUGACAAAGAACAUCAAGGCUCAAUCCUUGGAACUCUCCAUCACUCAUCUUUAAAUUAGACUUCUCUGCUGACUCUCAGAGUUGUGUAUGCUGAGAAUCCACUGCCUCUAAGACAUCCUGCUUGGCAGGUAACAGACAUUUCAUCCUGAGCUGAGCUCCUGCCCACCCCGCCCACACACAGACCCCUUCUUGCCCACAGAUUUCCCAUCUCAGCCAAUGGCGAGUCCAAAAAUCCUUUGUGUCCCCUUUGAUUCUUAGGUUCCUAUCUCCCUUCGACUGAGGCAUCGUUUCCAAAUCAGACACUUCUCGUCACCACUAUUGCCCUCCCCUUGUCCAACCCACCUUUGGCUCUUGGCUGGAGUCCGGUGAGUCUCCUAGCUGGCUCUCCCUGUUCUCGUCAUUUCCCAGUAAGUUCCAACCCUGCCUUCAGACUCUUCUGCACACAGCUUCCAGAGUAAUCCUUUCAAAAAGUAAGUCAGAUCCCAUCUUUUCCCUCCCGUCUCACUCUGUCAGCCACAUUCAUUCCAAAGGACCAUGUGGUCCAUGUCCCUGUUCUCUCUGGUUCUCUCACUGCUCUCCUCUGUGCUUACUCUCUCCUGCCUCACAAUGUUUGCACUUACUGUUUCUUCUGCUUGGAACUCUUUCCCUCCAAGACCUUUUUUUUUUGAGACGGAGUCUCGCUCUGUCGCCCAGGCUGGAGCGCAGUGGUGCAAUCUCUGCUCACUGCAAGCUCUGCCUCCCAGGUUCACGUCAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGACUACACGCACCAGCCACCAUACCCAGCUCAUUUUUUUUGUAUUUUCAGUAGAGACGGGGUUUCACCAUGUUGGCCAGGAUGGUCUUGAUCUCCUGACCUCGUGAUCCGCCCGCCUCGGCCUCCCUAAGCGCUGGGAUUACAGGUGUGAACCACCGCGCCCGGCCUCCCUCCAAGAUCUUUACUCACGUUGUCACCUUAGUGACGGCUCCCUCCCUAACCAUCCUAUUUAAAAUUGCAGCCCGUUCAACACCCAUUCCUCCUUCUCCAUCCUUGCUCUGCUUCCUCCCUUUGACCUGUCACUCUUUAAUCCAGUGGCAUUCUGAUUCAAUGGUGACUGGGAGCAGGACCUAAGGAGGUGCGUCAUCUGUAGAGAAUUUGAAAAUAAUCGUGAAAUAAACUCAAAGUGGGUUUGCUCUUUAUGAGCCCCGCACACCAGCAAUUCUAAAUUCUGUUAUCAAUAUACUUUCCUGCCAGGGUGGGCCGCCCCCACCGAUUCUCCUCUAUCUUAAUACACUAUGUGUUUCCCUUGUUUAUUUUGCUUAUUGUUCAUUUCCAUGCACUAGAAUAUAAGCUCCGCGAGGGCAGUAUAUUUUGUCUGUUUUGUUCACCACUGUGUCCCUCGUGUCUGCCACAUGGUGUGUGCUCAGUAAGCUUUAGCUGAAUGAAUGAAGUGGUGGAUGUCGACGUUCCCUUAGUUGGGGGUUAUCAGGAGGGCUUCCUGGAUGAAUUGGUGUCUAUAUUGCCUGUCCUUAAAGAGGAGGAAGGUGCUCUAGGCAGAAGGAACAGCAGGUACAAAAGCAACUUGACUGUCAGGGUCAUUAGCUAAGAGUAGGAGUCAGAGGGAUGAGUGGGUGUCGUUCACCAGAAUUUACCCUUCAAAAUGUCAGUGCUUAGUAAAUGAAUGUGUUCCUUUAUUACUAGUUGUUGGAGGGUCCUUGUUGACAUCUUGCAGAGGUCUGGCUGUCACUUUUAAUCAGAAUGGCUAUUCCCCACUCCUGCUGAAGAGCUCCAGGCCUGGCGGGGGUGGGCUGGCGGGCUGUGGUGGUGGUAAGGGCUGUCCCCCAGCACACUGUUAGAACUUUACUUAUCCUCUUGCUUGAAGUGUGGGAGCUGGAGACCAUUCAGGAAGCUGUGGUUACAGUCCCAGACAGGGUCCCUAAAAGCAAGGAGCCAUUCCCAAUGCUUCCUCCUUAGGGAAGCCUUCCCUACUUUCUCUUCCCUCUUCUGGGCAGAGUUUGUACCUUCCUCCUUUUUGCUCUCUGUUUAUUUCUUUAAUUUAACACUUAACAACAUAAUACCAUCUUUAUUUGUUCCAUGUUUGUAUCUUCUACUGAAUGUGGCUUCAAGAACAGAAAGCACAGAACGUGGCACGUUGGAGGAAAUCAGUAAGUGUUUGCUAAAGGUCCAACAAUGAAACAGAACAGAUAUAUCCAGUGCUAUGCCGCGUCAAAAGAGUAUGAGAGGUAUUGUGGUGAUGCUUUUGAAUGCUAAUCAGAAUAAGGAGGGUGACUAGUCCAUAGUUAUAUAGAAUAUAGGAUAUACAGAAUAUACCUUUUUCUGUAACGGGAUGUGUCACUUAACUUUGUUCCUUAAAGCUCCAGAAGCCCAAGGUCACCCACAAUGAUUCAAGUAUUAUCAAUGUUGAGAGCCUGUAAAAGCAUCAAGUAUAUUAUAGUUUCCAAAAAAUUGUGAAUUAGACUGAAAACCAGCAUUUAAAAAAUAAAGUGAUGUUGACUUAAAAAAAAAA

Taxonomic tree

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Publications